Babatunde Opeyemi, Forsyth Jacky
School of Psychology, Sport and Exercise Faculty of Health Sciences, Staffordshire University, Leek Road, Stoke On Trent, Staffordshire, ST4 2DF, UK,
J Bone Miner Metab. 2014 Sep;32(5):563-72. doi: 10.1007/s00774-013-0527-9. Epub 2013 Nov 8.
Osteoporosis, a slowly evolving public health epidemic, often with an insidious presentation is largely preventable but the optimal dimensions of exercise that may be prescribed for enhancing bone-health among premenopausal adults are yet to be elucidated. Hence, the escalating incidence and burden of prevalence of osteoporosis is yet unabated. Considering that exogenous hormones in the form of hormonal contraception are known to modulate bone mass, investigations of their possible influence on the translation of exercise-induced osteogenic stimuli on the mature bone is pertinent. The aim of this study was to examine the effect of specified lifestyle exercise on bone-health of premenopausal women. Premenopausal women (n = 96, mean age: 22.25 ± 3.5 years; mean BMI: 23.43 ± 3.5 kg/m(2)) participated in a 6-month randomised controlled trial involving home-based rest-interspersed bouts of high-impact exercise for the intervention group and sham exercise for the control group. Approximately half (47) of the participants (24-exercise, 23-control) were on hormonal-based contraception while the other half (49: 24-exercise, 25-control) were not on hormonal contraception. The regime led to a significant 3.7 % increase in broadband ultrasound attenuation of exercisers compared to controls; hormonal contraceptive use did not appear to potentiate the osteogenic effects of the lifestyle exercise regime. The research highlights that short, discrete bouts of high-impact exercise may be a potential public health prescription for enhancing premenopausal bone-health regardless of hormonal contraceptive use.
骨质疏松症是一种逐渐演变的公共卫生流行病，通常表现隐匿，很大程度上是可预防的，但对于绝经前成年人，为增强骨骼健康而规定的最佳运动规模尚未明确。因此，骨质疏松症的发病率和患病率负担仍在不断上升。鉴于已知激素避孕形式的外源激素会调节骨量，研究其对成熟骨上运动诱导的成骨刺激转化的可能影响是相关的。本研究的目的是检查特定生活方式运动对绝经前女性骨骼健康的影响。绝经前女性（n = 96，平均年龄：22.25 ± 3.5岁；平均BMI：23.43 ± 3.5 kg/m²）参加了一项为期6个月的随机对照试验，干预组进行在家中穿插休息的高强度冲击运动，对照组进行假运动。大约一半（47名）参与者（24名运动组，23名对照组）使用激素避孕，而另一半（49名：24名运动组，25名对照组）未使用激素避孕。与对照组相比，该运动方案使运动者的宽带超声衰减显著增加了3.7%；使用激素避孕似乎并未增强生活方式运动方案的成骨作用。该研究强调，无论是否使用激素避孕，短时间、分散的高强度冲击运动可能是增强绝经前骨骼健康的一种潜在公共卫生处方。
