Fine A M, Elman M J, Ebert J E, Prestia P A, Starr J S, Fine S L
Arch Ophthalmol. 1986 Apr;104(4):513-4. doi: 10.1001/archopht.1986.01050160069013.
One hundred three patients with neovascular maculopathy and relatively recent vision loss were surveyed to determine the most frequent symptoms and to assess the reliability of the Amsler grid in helping patients to detect early symptoms. Blurred vision and distortion, most often with near vision, were the most frequent first symptoms reported by patients. Of 49 patients who said that they were observing the Amsler grid on a regular basis, only five indicated that the Amsler grid abnormality was the first visual symptom. However, all but five of 49 patients did notice an Amsler grid abnormality during the office examination, suggesting noncompliance as the probable explanation for failure to detect an Amsler grid abnormality earlier. Patients at risk for neovascular maculopathy should be encouraged to assess a variety of visual functions--including reading vision, color saturation, and image clarity--in addition to observing the Amsler grid, in order to help them detect the earliest symptoms of submacular fluid from a potentially treatable neovascular membrane.
对103例患有新生血管性黄斑病变且视力近期下降的患者进行了调查，以确定最常见的症状，并评估阿姆斯勒方格表在帮助患者检测早期症状方面的可靠性。视力模糊和变形，最常见于近视力时，是患者报告的最常见的首发症状。在49例表示定期观察阿姆斯勒方格表的患者中，只有5例指出阿姆斯勒方格表异常是首个视觉症状。然而，49例患者中除5例之外的所有患者在诊室检查期间均注意到阿姆斯勒方格表异常，这表明不依从可能是未能更早检测到阿姆斯勒方格表异常的原因。除了观察阿姆斯勒方格表之外，还应鼓励有新生血管性黄斑病变风险的患者评估多种视觉功能，包括阅读视力、色彩饱和度和图像清晰度，以帮助他们检测来自潜在可治疗的新生血管膜的黄斑下液的最早症状。
