大鼠体内乙醛与心脏蛋白质合成

Acetaldehyde and cardiac protein synthesis in the rat in vivo.

作者信息

Auton W P, Ward L C

出版信息

Int J Biochem. 1986;18(3):289-92. doi: 10.1016/0020-711x(86)90122-9.

PMID:2420656

Abstract

Protein synthesis was measured in the hearts of rats exposed to acetaldehyde vapour for 21 days. Exposure to acetaldehyde significantly increased heart weight (expressed as % body weight) but was without effect on the rate of synthesis of mixed cardiac proteins. Concentrations of RNA in the hearts were not altered by acetaldehyde exposure, indicating no change in RNA activity for protein synthesis.

摘要

在暴露于乙醛蒸汽21天的大鼠心脏中测量蛋白质合成。暴露于乙醛显著增加了心脏重量（以体重百分比表示），但对混合心脏蛋白质的合成速率没有影响。乙醛暴露并未改变心脏中RNA的浓度，表明蛋白质合成的RNA活性没有变化。