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[妊娠期疑似良性卵巢肿瘤]

[Presumed benign ovarian tumors during pregnancy].

作者信息

Tariel O, Huissoud C, Rudigoz R C, Dubernard G

机构信息

Service de gynécologie-obstétrique, hôpital de la Croix-Rousse, 103, Grande-Rue-de-la-Croix-Rousse, 69004 Lyon, France; Université Claude-Bernard Lyon-1, 43, boulevard du 11-Novembre-1918, 69622 Villeurbanne cedex, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2013 Dec;42(8):842-55. doi: 10.1016/j.jgyn.2013.09.038. Epub 2013 Nov 7.

Abstract

The incidence of ovarian tumors diagnosed during pregnancy is between 0.3 and 5.4% (LE2). The most common ovarian tumors diagnosed during pregnancy are functional cysts diagnosed incidentally during the first trimester ultrasound (LE2) and spontaneous regression is often observed. Dermoid cysts and cystadenoma are the most frequent organic benign ovarian tumors diagnosed during pregnancy (LE2). The main complication of presumed benign ovarian tumor (PBOT) during pregnancy is adnexal torsion and is estimated at around 8% (LE2), especially at the end of the first trimester and during the second trimester (LE4). Tumor markers are not reliable during pregnancy to assess the risk of malignancy of ovarian tumor (LE2). Ultrasound remains the gold standard for characterizing an ovarian tumor during pregnancy (LE3), but with a lower specificity for the diagnosis of malignancy. Pelvic MRI is accurate in the diagnosis of ovarian tumors during pregnancy and brings additional information to ultrasound (LE4). Ultrasound-guided aspiration of ovarian tumors is not recommended during pregnancy (grade C). Expectation is recommended in cases of PBOT during pregnancy, which does not enlarge (grade C). Whatever the gestational age, surgery is recommended in patients with symptoms suggesting an adnexal torsion (grade C). Laparoscopy is possible during the first and second trimester of pregnancy for the management of symptomatic PBOT (LE3). The risk of miscarriage following surgery (laparoscopy and laparotomy) for ovarian tumor during pregnancy is estimated at 2.8% (LE3). The route of delivery should not be modified by the ovarian tumour, except in case of praevia cyst requiring a cesarean section, a complication or suspicion of malignancy (grade C). Surgical treatment of PBOT may be performed during a cesarean section indicated for another reason. The risk of torsion is increased during the postpartum period (LE4).

摘要

孕期诊断出卵巢肿瘤的发生率在0.3%至5.4%之间(证据等级2)。孕期诊断出的最常见卵巢肿瘤是在孕早期超声检查时偶然发现的功能性囊肿(证据等级2),且常观察到其自发消退。皮样囊肿和囊腺瘤是孕期诊断出的最常见的器质性良性卵巢肿瘤(证据等级2)。孕期疑似良性卵巢肿瘤(PBOT)的主要并发症是附件扭转,估计发生率约为8%(证据等级2),尤其在孕早期末和孕中期(证据等级4)。孕期肿瘤标志物在评估卵巢肿瘤恶性风险方面并不可靠(证据等级2)。超声仍然是孕期卵巢肿瘤特征性诊断的金标准(证据等级3),但对恶性肿瘤诊断的特异性较低。盆腔磁共振成像(MRI)在孕期卵巢肿瘤诊断中准确,可为超声检查提供额外信息(证据等级4)。孕期不建议超声引导下抽吸卵巢肿瘤(C级)。孕期PBOT未增大的病例建议观察(C级)。无论孕周如何,有附件扭转症状的患者建议手术(C级)。妊娠前两个月可行腹腔镜手术治疗有症状的PBOT(证据等级3)。孕期卵巢肿瘤手术后(腹腔镜和开腹手术)流产的风险估计为2.8%(证据等级3)。除了囊肿前置需要剖宫产、出现并发症或怀疑恶性肿瘤的情况外,分娩方式不应因卵巢肿瘤而改变(C级)。PBOT的手术治疗可在因其他原因行剖宫产时进行。产后附件扭转风险增加(证据等级4)。

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