Park J H, Ruiz M C, Shields D, Orr D J
Peripheral Vascular Unit, Western Infirmary, Glasgow, UK -
Int Angiol. 2013 Dec;32(6):593-8.
Aim of the study was to assess the effect of socioeconomic deprivation on prescribing of cardiovascular secondary prevention medications in patients referred with peripheral arterial disease (PAD).
A retrospective review of vascular clinic referrals was performed. All patients referred from primary care with suspected PAD over a two month period were included. The deprivation score, prescription of cardiovascular secondary prevention medications, smoking status and the presence of cardiovascular co-morbidities (coronary artery or cerebrovascular disease--CAD/CVD) were assessed. Comparison was made between socioeconomic groups using the Carstairs Deprivation (DepCat) Score and between patients with and without a history of currently existing cardiovascular co-morbidities.
The study included 391 patients. Almost two thirds of patients (253) were from the most deprived socioeconomic groups and were significantly younger at presentation (median age DepCat 7: 63 yrs, DepCat 1-2: 74.5 yrs, P<0.0001). The majority of patients with a prior history of CAD/CVD were prescribed secondary preventative medications at the time of referral with suspected PAD whereas those with no prior history of CAD/CVD, (212 patients, 54%) were significantly less likely to be prescribed antiplatelets (47% vs. 83%), statins (45% vs. 86%) or ACEi/ARBs (29% vs. 68%) (all P<0.05). Secondary prevention prescribing did not differ between socioeconomic groups.
Secondary prevention prescribing is inadequate in patients with suspected PAD regardless of socioeconomic group and is significantly lower in those without previously diagnosed CAD/CVD. There remains a lack of appreciation of the high cardiovascular risk associated with PAD.
本研究旨在评估社会经济剥夺对因外周动脉疾病(PAD)转诊患者心血管二级预防药物处方的影响。
对血管门诊转诊病例进行回顾性分析。纳入在两个月内从初级保健机构转诊的所有疑似PAD患者。评估其剥夺分数、心血管二级预防药物的处方情况、吸烟状况以及心血管合并症(冠状动脉或脑血管疾病——CAD/CVD)的存在情况。使用卡斯泰尔斯剥夺(DepCat)分数对社会经济群体进行比较,并对有和没有当前存在心血管合并症病史的患者进行比较。
该研究纳入了391名患者。近三分之二的患者(253名)来自社会经济最贫困群体,就诊时年龄显著更小(DepCat 7组的中位年龄:63岁,DepCat 1 - 2组:74.5岁,P<0.0001)。大多数有CAD/CVD病史的患者在因疑似PAD转诊时已开具二级预防药物,而那些没有CAD/CVD病史的患者(212名患者,54%)开具抗血小板药物(47%对83%)、他汀类药物(45%对86%)或ACEi/ARBs(29%对68%)的可能性显著更低(所有P<0.05)。社会经济群体之间的二级预防处方没有差异。
无论社会经济群体如何,疑似PAD患者的二级预防处方均不足,且在先前未诊断出CAD/CVD的患者中显著更低。对与PAD相关的高心血管风险仍缺乏认识。