银催化的邻炔基苯胺衍生物与2-三丁基锡烷基呋喃的串联环化-锡基化反应：(3-吲哚基)锡烷的高效合成
Silver-catalyzed cascade cyclization-stannylation of o-alkynylaniline derivatives with 2-tributylstannylfuran: an efficient synthesis of (3-indolyl)stannanes.
作者信息
Liu Jun, Xie Xin, Liu Yuanhong
机构信息
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling Ling Lu, Shanghai 200032, P. R. China.
出版信息
Chem Commun (Camb). 2013 Dec 28;49(100):11794-6. doi: 10.1039/c3cc46524a.
PMID:24213517
Abstract
A straightforward synthesis of (3-indolyl)stannanes through silver-catalyzed cyclization-stannylation of N-electron-withdrawing group-substituted o-alkynylanilines in the presence of 2-tributylstannylfuran is developed. This method offers several advantages such as no requirement of additional ligands, high efficiency and a wide reaction scope.
摘要
通过在2-三丁基锡烷基呋喃存在下，对N-吸电子基团取代的邻炔基苯胺进行银催化环化-锡基化反应，实现了(3-吲哚基)锡烷的直接合成。该方法具有无需额外配体、效率高和反应范围广等优点。
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