Mosley William J, Smith Michael R, Price Matthew J
Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, California.
Catheter Cardiovasc Interv. 2014 Mar 1;83(4):664-9. doi: 10.1002/ccd.25251. Epub 2013 Nov 9.
Left atrial appendage (LAA) occlusion or ligation is a novel approach to stroke prevention in atrial fibrillation that may obviate the need for long-term anticoagulation. The Lariat device has received Food and Drug Administration 510K clearance for the approximation of soft tissue and has been applied to transcatheter LAA ligation using a combined trans-pericardial and transseptal approach. The occurrence of late leak after transcatheter LAA ligation and its percutaneous management has not been previously reported. Herein, we report three cases of late leak with reconstitution of the LAA after initially successful Lariat closure, and present a simple percutaneous technique for leak closure.
左心耳（LAA）封堵或结扎是预防房颤患者中风的一种新方法，可能无需长期抗凝治疗。Lariat装置已获得美国食品药品监督管理局（FDA）的510K许可，可用于软组织贴合，并已应用于经皮心包和经房间隔联合入路的经导管LAA结扎术。经导管LAA结扎术后迟发性渗漏的发生及其经皮处理此前尚未见报道。在此，我们报告3例在最初成功使用Lariat闭合后LAA重建的迟发性渗漏病例，并介绍一种简单的经皮渗漏闭合技术。
