Bonnheim D C, Petrelli N J, Herrera L, Walsh D, Mittelman A
Am J Surg. 1986 Apr;151(4):457-9. doi: 10.1016/0002-9610(86)90102-9.
In a 10 year (1970 to 1980) retrospective study of 66 patients with primary colorectal adenocarcinoma and osseous metastases, there were 47 patients who had bone and other distant metastases whereas 19 patients had osseous metastases only. The median disease-free interval was 21 months. The overall median survival time from diagnosis of osseous metastases was 7 months. Bone scanning is probably more sensitive for diagnosing bone metastases that radiography. Radiotherapy seems to be the most effective treatment for symptomatic osseous metastases.
在一项为期10年(1970年至1980年)的回顾性研究中,对66例原发性结直肠癌伴骨转移患者进行了研究,其中47例患者有骨及其他远处转移,而19例患者仅有骨转移。无病间期的中位数为21个月。从骨转移诊断开始计算的总体中位生存时间为7个月。骨扫描对诊断骨转移可能比X线摄影更敏感。放疗似乎是治疗有症状骨转移最有效的方法。