Smart I J, Embury D H, Barr D A, Sinclair A J, Karunajeewa H, Ewing I, Reece R L, Forsyth W M, Hooper P T
Avian Dis. 1985 Oct-Dec;29(4):1201-11.
The role of selenium deficiency in the etiology of the runting-stunting syndrome (RSS) of broiler chickens in Australia was investigated. Commercial broiler chickens maintained on selenium-deficient developed signs consistent with selenium deficiency of exudative diathesis and markedly reduced plasma glutathione peroxidase activity, but they did not develop pancreatic atrophy and fibrosis or elevated plasma amylase activity, which are the other lesions associated with RSS. Supplementation of the diets of birds from a RSS-susceptible flock with a mixture of selenium, vitamin E, cysteine, and sulfate had no effect on the incidence of runting in the treated birds. In field outbreaks of RSS there were no observable differences between affected and unaffected birds in the concentration of selenium in tissue samples. Furthermore, evidence is presented which suggests that in cases of RSS, pancreatic atrophy and elevations in plasma amylase precede reductions in plasma glutathione peroxidase activity.
对澳大利亚肉鸡发育不良综合征（RSS）病因中硒缺乏的作用进行了调查。在缺硒环境下饲养的商品肉鸡出现了与渗出性素质的硒缺乏相一致的症状，血浆谷胱甘肽过氧化物酶活性显著降低，但它们并未出现胰腺萎缩和纤维化或血浆淀粉酶活性升高的情况，而这些是与RSS相关的其他病变。用硒、维生素E、半胱氨酸和硫酸盐的混合物补充易感RSS鸡群的日粮，对治疗鸡群的发育不良发生率没有影响。在RSS的田间爆发中，受影响和未受影响的鸡在组织样本中的硒浓度没有可观察到的差异。此外，有证据表明，在RSS病例中，胰腺萎缩和血浆淀粉酶升高先于血浆谷胱甘肽过氧化物酶活性降低。
