From the Department of Radiology, Washington DC VA Medical Center, Washington, DC.
Clin Nucl Med. 2014 Sep;39(9):e407-9. doi: 10.1097/RLU.0000000000000285.
We present different findings on 18F-FDG PET/CT and 18F-NaF PET/CT images in 2 patients with multiple myeloma. In 1 case, 18F-FDG PET/CT showed intense uptake in the lesions in the axial skeleton where 18F-NaF PET/CT seemed normal. In addition, a sternal lesion showed FDG uptake only in the center but NaF uptake only in the periphery. In another patient, intense NaF accumulation in a dorsal vertebra was noted, but the corresponding FDG uptake was unimpressive. The role of these 2 radioactive tracers in the management of multiple myeloma continues to be defined.
我们在 2 例多发性骨髓瘤患者的 18F-FDG PET/CT 和 18F-NaF PET/CT 图像上呈现出不同的发现。在 1 例患者中，18F-FDG PET/CT 在轴性骨骼的病变部位显示出强烈摄取，而 18F-NaF PET/CT 似乎正常。此外，胸骨病变仅在中心部位显示 FDG 摄取，而仅在外围部位摄取 NaF。在另一位患者中，背部椎骨有强烈的 NaF 积聚，但相应的 FDG 摄取并不明显。这两种放射性示踪剂在多发性骨髓瘤治疗中的作用仍在不断明确。
