From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Clin Nucl Med. 2014 Apr;39(4):358-9. doi: 10.1097/RLU.0b013e31828e98c5.
Neuroendocrine tumors (NETs) are rare tumors which express somatostatin receptors (SSTRs). We here present a case of a 50-year-old female patient with metastatic bronchial carcinoid. She underwent 68Ga-DOTANOC PET/CT and 18F-FDG PET/CT which suggested a diagnosis of poorly differentiated NET. Biopsy of the lesion, however, revealed a second malignancy in the form of diffuse large B-cell lymphoma. Thus, very rarely, other primary tumors can mimic NETs on dual-tracer PET/CT, and biopsy is advised in doubtful cases.
神经内分泌肿瘤（NET）是一种罕见的肿瘤，表达生长抑素受体（SSTR）。我们在此介绍一例 50 岁女性转移性支气管类癌患者。她接受了 68Ga-DOTANOC PET/CT 和 18F-FDG PET/CT 检查，结果提示分化差的 NET 诊断。然而，病变活检显示为弥漫性大 B 细胞淋巴瘤的第二种恶性肿瘤。因此，在双重示踪剂 PET/CT 上，其他原发性肿瘤很少会模拟 NET，在可疑病例中建议进行活检。
