Munnecke D M, Hsieh D P
Appl Microbiol. 1975 Oct;30(4):575-80. doi: 10.1128/am.30.4.575-580.1975.
A mixed bacterial culture was adapted to growth on a mixed carbon substrate consisting of the pesticide parathion and its xylene-based formulation. The environmental growth parameters of temperature, pH, and dissolved oxygen concentration were optimized to obtain complete metabolism of parathion from this mixed carbon substrate. This adapted culture grew rapidly (mu = 0.7 per h) on the pesticide formulation at high parathion suspensions (3,000 mg/liter). Carbon utilization from this mixed substrate was strongly dependent on pH. At slightly acidic pH, xylene was preferentially metabolized, whereas at slightly alkaline pH, parathion was preferentially metabolized. Diethylthiophosphoric acid, a metabolite from parathion, and toluic acid, a metabolite from xylene, also influenced the selection of the primary carbon source.
一种混合细菌培养物适应了在由农药对硫磷及其基于二甲苯的制剂组成的混合碳底物上生长。对温度、pH值和溶解氧浓度等环境生长参数进行了优化，以实现对硫磷从这种混合碳底物中的完全代谢。这种适应的培养物在高对硫磷悬浮液（3000毫克/升）的农药制剂上生长迅速（μ = 每小时0.7）。从这种混合底物中对碳的利用在很大程度上取决于pH值。在略呈酸性的pH值下，二甲苯优先被代谢，而在略呈碱性的pH值下，对硫磷优先被代谢。对硫磷的代谢产物二乙基硫代磷酸和二甲苯的代谢产物甲苯酸也影响了主要碳源的选择。
