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宫腔镜输卵管绝育术:卫生经济学文献综述

Hysteroscopic tubal sterilization: a health economic literature review.

出版信息

Ont Health Technol Assess Ser. 2013 Oct 1;13(22):1-25. eCollection 2013.

Abstract

BACKGROUND

Hysteroscopic sterilization is a minimally invasive alternative to laparoscopic tubal ligation for women who want permanent contraception. In contrast to the laparoscopic technique, a hysteroscope is used to pass permanent microinserts through the cervix and place them in the fallopian tubes. This procedure does not require local or general anesthesia and can be performed in an office setting.

OBJECTIVES

The objective of this analysis was to determine, based on published literature, the cost-effectiveness of hysteroscopic tubal sterilization (HS) compared with laparoscopic tubal ligation (LS) for permanent female sterilization.

DATA SOURCES

A systematic literature search was conducted for studies published between January 1, 2008, and December 11, 2012.

REVIEW METHODS

Potentially relevant studies were identified based on the title and abstract. Cost-utility analyses (studies that report outcomes in terms of costs and quality-adjusted life-years) were prioritized for inclusion. When not available, cost-effectiveness, cost-benefit, and cost-consequence analyses were considered. Costing studies were considered in the absence of all other analyses.

RESULTS

A total of 33 abstracts were identified. Three cost analyses were included. A retrospective chart review from Canada found that HS was $111 less costly than LS; a prospective activity-based cost management study from Italy reported that it was €337 less costly than LS; and the results of an American decision model showed that HS was $1,178 less costly than LS.

LIMITATIONS

All studies had limited applicability to the Ontario health care system due to differences in setting, resource use, and costs.

CONCLUSIONS

Three cost analyses found that, although the HS procedure was more expensive due to the cost of the microinserts, HS was less costly than LS overall due to the shorter recovery time required.

PLAIN LANGUAGE SUMMARY

Hysteroscopic sterilization is a minimally invasive alternative to conventional tubal ligation for women who want a permanent method of contraception. Both approaches involve closing off the fallopian tubes, preventing the egg from moving down the tube and the sperm from reaching the egg. Tubal ligation is a surgical procedure to tie or seal the fallopian tubes, and it usually requires general anesthesia. In contrast, hysteroscopic tubal sterilization can be performed in 10 minutes in an office setting without general or even local anesthesia. A tiny device called a microinsert is inserted into each fallopian tube through the vagina, cervix, and uterus without surgery. An instrument called a hysteroscope allows the doctor to see inside the body for the procedure. Once the microinserts are in place, scar tissue forms around them and blocks the fallopian tubes. Health Quality Ontario commissioned a systematic review of published economic literature to determine whether hysteroscopic sterilization is cost-effective compared to tubal ligation. This review did not find any studies that reported results in terms of both costs and effectiveness or costs and quality-adjusted life-years. We did find 3 costing studies and included them in our review. All of these studies found that when hysteroscopic sterilization was performed as an outpatient procedure, it was less expensive than tubal ligation due to a shorter recovery time. However, none of the studies apply directly to Ontario because of differences in our health care system compared to those in the studies.

摘要

背景

对于希望采用永久性避孕方法的女性而言,宫腔镜绝育术是腹腔镜输卵管结扎术的一种微创替代方法。与腹腔镜技术不同,宫腔镜用于将永久性微插入物穿过宫颈并放置在输卵管中。该手术无需局部或全身麻醉,可在门诊进行。

目的

本分析的目的是根据已发表的文献,确定宫腔镜输卵管绝育术(HS)与腹腔镜输卵管结扎术(LS)相比用于永久性女性绝育的成本效益。

数据来源

对2008年1月1日至2012年12月11日期间发表的研究进行了系统的文献检索。

综述方法

根据标题和摘要确定潜在相关研究。优先纳入成本效用分析(报告成本和质量调整生命年结果的研究)。若无法获取此类分析,则考虑成本效果分析、成本效益分析和成本后果分析。在没有其他所有分析的情况下考虑成本核算研究。

结果

共识别出33篇摘要。纳入了三项成本分析。加拿大的一项回顾性病历审查发现,HS的成本比LS低111美元;意大利的一项基于活动的前瞻性成本管理研究报告称,HS的成本比LS低337欧元;美国一项决策模型的结果显示,HS的成本比LS低1178美元。

局限性

由于环境、资源使用和成本的差异,所有研究对安大略省医疗保健系统的适用性有限。

结论

三项成本分析发现,尽管由于微插入物的成本,HS手术费用更高,但由于所需的恢复时间较短,HS总体成本低于LS。

通俗易懂的总结

对于希望采用永久性避孕方法的女性,宫腔镜绝育术是传统输卵管结扎术的一种微创替代方法。两种方法都涉及封闭输卵管,阻止卵子沿输卵管下行以及精子与卵子结合。输卵管结扎是一种结扎或封闭输卵管的外科手术,通常需要全身麻醉。相比之下,宫腔镜输卵管绝育术可在门诊10分钟内完成,无需全身甚至局部麻醉。一种称为微插入物的微小装置通过阴道、宫颈和子宫插入每个输卵管,无需手术。一种称为宫腔镜的器械使医生能够在手术过程中看到体内情况。一旦微插入物就位,周围就会形成瘢痕组织并阻塞输卵管。安大略省卫生质量部委托对已发表的经济文献进行系统综述,以确定与输卵管结扎相比,宫腔镜绝育术是否具有成本效益。该综述未发现任何同时报告成本与效果或成本与质量调整生命年结果的研究。我们确实找到了3项成本核算研究并将其纳入综述。所有这些研究都发现,当宫腔镜绝育术作为门诊手术进行时,由于恢复时间较短,其成本低于输卵管结扎术。然而,由于我们的医疗保健系统与研究中的系统存在差异,这些研究均不能直接应用于安大略省。

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