Kumagai Youichi, Nagata Koji, Ishiguro Toru, Haga Norihiro, Kuwabara Kohki, Sobajima Jun, Kumamoto Kensuke, Ishibashi Keiichiro, Baba Hiroyuki, Shimizu Michio, Tamaru Jun-ichi, Kawano Tatsuyuki, Takubo Kaiyo, Ishida Hideyuki
1 Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Int Surg. 2013 Oct-Dec;98(4):450-4. doi: 10.9738/CC195.
This retrospective study investigated the clinicopathologic characteristics and clinical outcomes of esophageal basaloid squamous carcinoma (BSC). Among 190 patients with esophageal carcinoma treated surgically between 1998 and 2011, we identified 9 (4.7%) with BSC. All of the patients were male, with a median age of 65 years. The frequencies of venous invasion, lymphatic invasion, and lymph node metastasis were 56%, 89%, and 67%, respectively. A total of 2 patients were pathologic stage 1, 5 were stage 2, and 2 were stage 3. Tumor recurrence was observed in 56% of the patients. The 5-year survival rate for patients with esophageal BSC was 40%, which was compatible with the figure of 53.8% for control patients (n = 18) with typical squamous cell carcinoma matched for sex, age, tumor location, and pathologic stage (P = 0.45). Although esophageal BSC shows aggressive lymph-vascular invasion and has a high likelihood of recurrence, its prognosis seems identical to that of typical squamous cell carcinoma.
这项回顾性研究调查了食管基底样鳞状细胞癌（BSC）的临床病理特征和临床结局。在1998年至2011年间接受手术治疗的190例食管癌患者中，我们识别出9例（4.7%）为BSC。所有患者均为男性，中位年龄为65岁。静脉侵犯、淋巴侵犯和淋巴结转移的发生率分别为56%、89%和67%。共有2例患者为病理1期，5例为2期，2例为3期。56%的患者出现肿瘤复发。食管BSC患者的5年生存率为40%，这与按性别、年龄、肿瘤位置和病理分期匹配的18例典型鳞状细胞癌对照患者53.8%的生存率相当（P = 0.45）。尽管食管BSC表现出侵袭性的淋巴血管侵犯且复发可能性高，但其预后似乎与典型鳞状细胞癌相同。
