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一项针对澳大利亚女性使用皮下避孕植入物或释放孕激素的宫内节育系统的续用率、出血模式及满意度的三年比较研究。

A three-year comparative study of continuation rates, bleeding patterns and satisfaction in Australian women using a subdermal contraceptive implant or progestogen releasing-intrauterine system.

作者信息

Weisberg Edith, Bateson Deborah, McGeechan Kevin, Mohapatra Lita

机构信息

* Sydney Centre for Reproductive Health Research , FPNSW, Sydney , Australia.

出版信息

Eur J Contracept Reprod Health Care. 2014 Feb;19(1):5-14. doi: 10.3109/13625187.2013.853034. Epub 2013 Nov 14.

DOI:10.3109/13625187.2013.853034
PMID:24229367
Abstract

BACKGROUND Long-acting reversible contraceptive methods (LARCs) are safe, highly effective, readily reversible, and require no action on the part of the user following insertion. Early discontinuation may put women at increased risk of unintended pregnancy. METHODS Following insertion of a progestogen-only subdermal implant or intrauterine system (IUS) at Family Planning NSW, women 18 years and older completed a questionnaire about their choice. At 6 weeks, 6, 12, 24 and 36 months by telephone or online they completed a questionnaire about bleeding patterns, side effects, satisfaction, and reasons for discontinuation. RESULTS Two hundred IUS users and 149 implant users were enrolled. The former were generally older, married or in a de-facto relationship, and had children. Forty-seven percent of implant users discontinued within three years compared to 27% of IUS users (p = 0.002). In the first two years amenorrhoea was more frequent in implant users. Frequent bleeding/spotting was more prevalent in the first year of IUS use but over time was twice as prevalent in implant users. Infrequent bleeding/spotting was more common in IUS users. CONCLUSION Both devices are highly effective and acceptable cost-effective methods. While LARCs should be promoted to women of all ages seeking contraception, early discontinuation due to unacceptable bleeding highlights the need for pre-insertion counselling.

摘要

背景

长效可逆避孕方法(LARCs)安全、高效、易于恢复,且在植入后使用者无需采取任何行动。早期停用可能会增加女性意外怀孕的风险。

方法

在新南威尔士州计划生育中心植入仅含孕激素的皮下植入剂或宫内节育系统(IUS)后,18岁及以上的女性完成了一份关于其选择的问卷。在第6周、6个月、12个月、24个月和36个月时,她们通过电话或网络完成了一份关于出血模式、副作用、满意度及停用原因的问卷。

结果

招募了200名IUS使用者和149名植入剂使用者。前者通常年龄较大,已婚或处于事实婚姻关系,且育有子女。三年内在植入剂使用者中有47%停用,而IUS使用者中这一比例为27%(p = 0.002)。在头两年,植入剂使用者中闭经更为常见。频繁出血/点滴出血在IUS使用的第一年更为普遍,但随着时间推移,在植入剂使用者中更为普遍,是IUS使用者的两倍。不频繁出血/点滴出血在IUS使用者中更为常见。

结论

两种装置都是高效且可接受的具有成本效益的方法。虽然应向所有寻求避孕的年龄段女性推广LARCs,但因无法接受的出血导致的早期停用凸显了植入前咨询的必要性。

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