Short Mary, Dallay Dominique, Omokanye Salmon, Stauch Kathrin, Inki Pirjo
* Rock Court Medical Centre, Blackrock , Co. Dublin , Ireland.
Eur J Contracept Reprod Health Care. 2014 Feb;19(1):29-38. doi: 10.3109/13625187.2013.862230. Epub 2013 Nov 29.
OBJECTIVES To compare two-year continuation rates and user satisfaction with the levonorgestrel releasing-intrauterine system (LNG-IUS) and the etonogestrel releasing-subdermal implant (ENG implant) in women in Europe. METHODS This prospective, non-interventional study was undertaken at 72 sites in France (n = 61), Great Britain (n = 2), Ireland (n = 3) and Slovakia (n = 6). Women opting to switch their method of contraception to the LNG-IUS or the ENG implant were followed-up over 24 months to document continuation and satisfaction with their chosen contraceptive method. Reasons for discontinuation were documented. RESULTS The data analysed were based on 363 women (LNG-IUS [n = 247] and ENG implant [n = 116]), aged 20 to 45 years, with at least one follow-up visit after contraceptive placement. The documented cumulative continuation rate was 82% in the LNG-IUS group and 67% in the ENG implant group at 24 months. The documented discontinuation rates were 13% and 17%, respectively. Bleeding problems were cited as reason for discontinuation in 4% and 11% of women in the LNG-IUS and ENG implant groups, respectively. CONCLUSIONS The LNG-IUS is associated with higher continuation rates and user satisfaction than the ENG implant in this study of women in Europe, though the groups were not similar in all respects. Bleeding problems with the ENG implant account for most of the reasons for discontinuing its use.
目的 比较欧洲女性使用左炔诺孕酮宫内节育系统（LNG-IUS）和依托孕烯皮下埋植剂（ENG 埋植剂）的两年续用率及用户满意度。方法 这项前瞻性、非干预性研究在法国的 61 个地点、英国的 2 个地点、爱尔兰的 3 个地点和斯洛伐克的 6 个地点开展。选择将避孕方法转换为 LNG-IUS 或 ENG 埋植剂的女性接受了 24 个月的随访，以记录她们对所选避孕方法的续用情况和满意度。记录了停用原因。结果 分析的数据基于 363 名年龄在 20 至 45 岁之间的女性（LNG-IUS 组 247 名，ENG 埋植剂组 116 名），她们在放置避孕装置后至少接受了一次随访。记录的 24 个月累积续用率在 LNG-IUS 组为 82%，在 ENG 埋植剂组为 67%。记录的停用率分别为 13%和 17%。LNG-IUS 组和 ENG 埋植剂组分别有 4%和 11%的女性将出血问题作为停用原因。结论 在这项针对欧洲女性的研究中，LNG-IUS 与比 ENG 埋植剂更高的续用率和用户满意度相关，尽管两组在所有方面并不相似。ENG 埋植剂的出血问题是停用其使用的主要原因。
