Wei Li, Lu Yong-Yi, Qiao Li-Na, Hua Yi-Min, Wang Yi-Bin, Wang Xiao, Li Xin-Hui
Department of Pediatrics, West China Second Hospital of Sichuan University, Chengdu 610041, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2013 Nov;15(11):1014-7.
To investigate the significance of Tp-Te interval for risk stratification of ventricular premature contractions (VPC) in children.
A total of 120 children with VPC were divided into benign VPC (n=40), organic disease (n=40) and ventricular parasystole groups (n=40) according to the etiology of VPC; another 40 children who underwent physical examination were selected as the normal control group. The four groups were compared in terms of Tp-Te intervals and Tp-Te/QT ratios in leads V3, V4 and V5.
The Tp-Te interval in lead V3 was significantly longer in the organic disease group than in the other groups (P<0.05), the benign VPC group had a significantly shorter Tp-Te interval in lead V4 than the normal control and organic disease groups (P<0.05), and the organic disease group had a significantly longer Tp-Te interval in lead V5 than the benign VPC group (P<0.05). The Tp-Te/QT ratios in leads V3-V5 were significantly higher in the organic disease group than in the other groups (P<0.05). The Tp-Te/QT ratios in leads V4 and V5 showed significant differences between the ventricular parasystole and benign VPC groups (P<0.05).
Tp-Te interval is susceptible to changes in heart rate, and it is of little value for the risk stratification of VPC in children. Tp-Te/QT ratio, however, may be used as an important non-invasive index for clinical risk stratification of VPC in children and is worthy of further study.
探讨Tp-Te间期对儿童室性早搏(VPC)危险分层的意义。
将120例VPC患儿按病因分为良性VPC组(n=40)、器质性疾病组(n=40)和室性并行心律组(n=40);另选40例体检儿童作为正常对照组。比较四组V3、V4和V5导联的Tp-Te间期及Tp-Te/QT比值。
器质性疾病组V3导联的Tp-Te间期显著长于其他组(P<0.05),良性VPC组V4导联的Tp-Te间期显著短于正常对照组和器质性疾病组(P<0.05),器质性疾病组V5导联的Tp-Te间期显著长于良性VPC组(P<0.05)。器质性疾病组V3-V5导联的Tp-Te/QT比值显著高于其他组(P<0.05)。室性并行心律组与良性VPC组V4、V5导联的Tp-Te/QT比值有显著差异(P<0.05)。
Tp-Te间期易受心率变化影响,对儿童VPC危险分层价值不大。然而,Tp-Te/QT比值可作为儿童VPC临床危险分层的重要无创指标,值得进一步研究。