Wissner Erik, Metzner Andreas, Reissmann Bruno, Rausch Peter, Bardyszewski Aleksander, Lemes Christine, Tilz Roland Richard, Rillig Andreas, Mathew Shibu, Deiss Sebastian, Ouyang Feifan, Kuck Karl-Heinz
Department of Cardiology, Asklepios-Klinik St. Georg, Hamburg, Germany.
J Cardiovasc Electrophysiol. 2014 Mar;25(3):253-8. doi: 10.1111/jce.12326. Epub 2013 Dec 16.
The endoscopic ablation system (EAS) allows for effective pulmonary vein isolation (PVI). The feasibility of wide circumferential as compared to individual PVI using the EAS has not been formally assessed.
Patients with paroxysmal or short-persistent atrial fibrillation were assigned to individual PVI (group A) or wide circumferential PVI (group B). In group B, circumferential PVI was attempted only if the ipsilateral inferior PV was visualized while the ablation system targeted the superior PV and vice versa. Otherwise, individual PVI was performed.
A total of 38 patients were enrolled (Group A: 20 patients, age 61 ± 7 years, LA-diameter 43 ± 5 mm; Group B: 18 patients, age 62 ± 10 years, LA-diameter 43 ± 4 mm). In group A, 20/20 (100%) right superior (RSPV) and inferior (RIPV) PVs, 18/19 (95%) left superior (LSPV) and inferior (LIPV) PVs, and 1/1 (100%) left common ostium (LCPV) were successfully isolated. First-pass success rate was 95%, 85%, 68%, and 95% for the RSPV, RIPV, LSPV, and LIPV, respectively. Touch-up radiofrequency ablation was required in 1/19 (5%) LSPV and LIPV. In group B, an attempt at circumferential PVI was feasible in 2/18 (11%) septal PVs and successful on first pass. Lateral circumferential PVI was attempted and successful on first-pass in 7/13 (54%) LSPVs and LIPVs and 1/5 (20%) LCPVs.
Using the EAS in patients with AF, separate isolation of individual PVs rather than wide circumferential PVI should be the preferred ablation strategy.
内镜消融系统(EAS)可实现有效的肺静脉隔离(PVI)。与使用EAS进行单个肺静脉隔离相比,广泛环周肺静脉隔离的可行性尚未得到正式评估。
将阵发性或短程持续性房颤患者分为单个肺静脉隔离组(A组)或广泛环周肺静脉隔离组(B组)。在B组中,仅当同侧下肺静脉可见时才尝试环周肺静脉隔离,此时消融系统靶向肺静脉,反之亦然。否则,进行单个肺静脉隔离。
共纳入38例患者(A组:20例患者,年龄61±7岁,左心房直径43±5mm;B组:18例患者,年龄62±10岁,左心房直径43±4mm)。在A组中,20/20(100%)的右上肺静脉(RSPV)和右下肺静脉(RIPV)、18/19(95%)的左上肺静脉(LSPV)和左下肺静脉(LIPV)以及1/1(100%)的左肺总静脉(LCPV)成功隔离。RSPV、RIPV、LSPV和LIPV的首次通过成功率分别为95%、85%、68%和95%。1/19(5%)的LSPV和LIPV需要进行补针射频消融。在B组中,2/18(11%)的间隔肺静脉尝试环周肺静脉隔离且首次通过成功。7/13(54%)的LSPV和LIPV以及1/5(20%)的LCPV尝试并首次通过成功进行了外侧环周肺静脉隔离。
在房颤患者中使用EAS时,首选的消融策略应是单独隔离单个肺静脉,而非广泛环周肺静脉隔离。