儿童巨大先天性黑素细胞痣中的神经皮肤黑色素沉着症。
Neurocutaneous melanosis in children with giant congenital melanocytic nevi.
机构信息
Department of Diagnostic Imaging, Institute of Mother and Child, ul. Kasprzaka 17a, 01-211 Warsaw, Poland.
Clinic of Surgery of Children and Adolescents, Institute of Mother and Child, ul. Kasprzaka 17a, 01-211 Warsaw, Poland.
出版信息
Clin Imaging. 2014 Mar-Apr;38(2):79-84. doi: 10.1016/j.clinimag.2013.10.001. Epub 2013 Oct 16.
Twenty-four children with giant congenital melanocytic nevi underwent brain MRI at 1.5 T scanner. Melanin deposits in the brain were found in seven children (29.2%) located in temporal lobes, thalamus, cerebellum, and pons. One patient showed leptomeningeal involvement. Six patients were asymptomatic, and one had epilepsy. As opposed to previous reports, localization of skin nevi on anterior part of trunk was correlated to central nervous system involvement. In all patients with brain involvement skin nevi showed picture of compound nevus with neurofibromatic component.
24 名患有巨大先天性黑色素痣的儿童在 1.5T 扫描仪上进行了脑部 MRI 检查。在 7 名儿童（29.2%）中发现了脑部的黑色素沉积，位于颞叶、丘脑、小脑和脑桥。一名患者出现软脑膜受累。6 名患者无症状，1 名患者患有癫痫。与之前的报告相反，躯干前部的皮肤痣定位与中枢神经系统受累有关。所有脑部受累的患者皮肤痣均显示具有神经纤维瘤成分的复合痣图像。
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