Department of Pediatrics, University of Michigan, Ann Arbor, Michigan.
Biol Blood Marrow Transplant. 2014 Feb;20(2):149-53. doi: 10.1016/j.bbmt.2013.11.006. Epub 2013 Nov 12.
Outcomes of hematopoietic cell transplantation continue to improve. New techniques have reduced transplant toxicities, and there are new sources of hematopoietic stem cells from related and unrelated donors. In June 2007, the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) convened a State of the Science Symposium (SOSS) in Ann Arbor and identified 11 high priority clinical trials for the network to pursue. This article reviews both the status of those trials and the record of achievement of the BMT CTN as it convenes another SOSS in Grapevine, Texas in February 2014.
造血细胞移植的疗效不断提高。新技术降低了移植的毒性，也有来自亲缘和非亲缘供者的新的造血干细胞来源。2007 年 6 月，血液和骨髓移植临床研究网络（BMT CTN）在安阿伯举行了一次科学状况研讨会（SOSS），确定了该网络需要进行的 11 项优先临床试验。本文回顾了这些试验的现状以及 BMT CTN 的成就，因为该网络于 2014 年 2 月在德克萨斯州的 Grapevine 再次召开了 SOSS。
