低亲和力和高亲和力γ-氨基丁酸（GABA）受体可能参与氯离子流入突触体的过程。
Possible involvement of low and high affinity GABA receptors in the chloride influx into synaptosomes.
作者信息
Sánchez C, Giménez A, Cañadas S, González M P
出版信息
Rev Esp Fisiol. 1986 Mar;42(1):1-5.
PMID:2424059
Abstract
Experiments carried out in the absence or presence of GABA using a synaptosomal fraction from which endogenous GABA was as far as possibly eliminated, seem to indicate that both GABA receptors are involved in the chloride channel opening. This hypothesis is supported by results obtained in the presence of GABA agonist (muscimol) or drugs which are related to the complex GABA receptor-ionophore (diazepam and phenobarbital).
摘要
利用尽可能去除内源性γ-氨基丁酸（GABA）的突触体组分，在有无GABA的情况下进行的实验似乎表明，两种GABA受体都参与了氯离子通道的开放。在存在GABA激动剂（蝇蕈醇）或与复杂的GABA受体-离子载体相关的药物（地西泮和苯巴比妥）时所获得的结果支持了这一假说。
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