伴有脊髓髓内受累的脑淋巴瘤病。
Lymphomatosis cerebri with intramedullary spinal cord involvement.
作者信息
Sato Hiroyasu, Takahashi Yoshimi, Wada Manabu, Shiono Yousuke, Suzuki Ikuko, Kohno Kei, Kato Yuichi, Kawanami Toru, Sakurada Kaori, Kayama Takamasa, Kato Takeo
机构信息
Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Japan.
出版信息
Intern Med. 2013;52(22):2561-5. doi: 10.2169/internalmedicine.52.0748.
Lymphomatosis cerebri (LC) is a rare form of primary central nervous system lymphoma (PCNSL). Little is known about cases of LC with spinal cord involvement. Among the 11 PCNSL patients treated in our hospital during a four-year period, we identified two cases of LC with spinal cord lesions. One showed a spinal cord lesion followed by leukoencephalopathy. The other showed a spinal cord lesion after LC. In both cases, the histopathology was diffuse large B-cell lymphoma. It is possible that LC may affect the entire central nerve system, and tumor infiltration to the brain and spinal cord in LC may occur more frequently than has been previously considered.
脑淋巴瘤病（LC）是原发性中枢神经系统淋巴瘤（PCNSL）的一种罕见形式。关于合并脊髓受累的LC病例，人们了解甚少。在我院四年期间治疗的11例PCNSL患者中，我们发现了2例合并脊髓病变的LC病例。1例表现为脊髓病变后出现白质脑病。另1例表现为LC后出现脊髓病变。两例组织病理学均为弥漫性大B细胞淋巴瘤。LC可能会累及整个中枢神经系统，并且LC中肿瘤浸润至脑和脊髓的情况可能比之前认为的更常见。
Zotero 插件