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对一名患有转移性睾丸癌的肾移植受者采用铂类细胞毒性药物进行的根治性治疗。

Curative, platinum-based cytoxic drug therapy in a renal transplant recipient with metastatic testicular cancer.

作者信息

Osiason A W, Polackwich R J

出版信息

Cancer. 1986 Aug 15;58(4):850-1. doi: 10.1002/1097-0142(19860815)58:4<850::aid-cncr2820580407>3.0.co;2-r.

DOI:10.1002/1097-0142(19860815)58:4<850::aid-cncr2820580407>3.0.co;2-r
PMID:2424586
Abstract

Since June 1979, the authors have had the opportunity to treat a renal homograph recipient who developed primary embryonal cell testicular carcinoma with retroperitoneal and pulmonary metastases. This patient was treated with an induction chemotherapy protocol of vinblastine sulfate, bleomycin, and cisplatin and has remained free of disease through June 1985, without loss of his renal homograph. Cisplatin-based cytoxic drug therapy can be delivered safely to a renal transplant recipient without causing kidney damage, and, in this case, achieved a cure of metastatic testicular cancer.

摘要

自1979年6月以来,作者们有机会治疗一名肾移植受者,该受者发生了原发性胚胎细胞睾丸癌并伴有腹膜后和肺部转移。该患者接受了硫酸长春碱、博来霉素和顺铂的诱导化疗方案治疗,截至1985年6月一直无病生存,且其肾移植未失功。基于顺铂的细胞毒性药物治疗可安全用于肾移植受者而不造成肾损害,在本病例中,实现了转移性睾丸癌的治愈。

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Curative, platinum-based cytoxic drug therapy in a renal transplant recipient with metastatic testicular cancer.对一名患有转移性睾丸癌的肾移植受者采用铂类细胞毒性药物进行的根治性治疗。
Cancer. 1986 Aug 15;58(4):850-1. doi: 10.1002/1097-0142(19860815)58:4<850::aid-cncr2820580407>3.0.co;2-r.
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Effects of multiple-drug chemotherapy (cis-diammine-dichloroplatinum, bleomycin, and vinblastine) on the maturation of retroperitoneal lymph node metastases of nonseminomatous germ cell tumors of the testis. No evidence for De Novo induction of differentiation.
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Second malignancy after cisplatin, vinblastine, and bleomycin (PVB) chemotherapy: a case report.顺铂、长春碱和博来霉素(PVB)化疗后发生的第二原发性恶性肿瘤:一例报告。
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