Best J F, Rinkenberger R, Lynch L, Dunn M
Clin Cardiol. 1986 Jun;9(6):268-71. doi: 10.1002/clc.4960090607.
Amiodarone was used in the treatment of 21 patients with supraventricular or ventricular arrhythmias which were refractory to conventional antiarrhythmic drugs, individually or in combination. Six of seven patients with supraventricular arrhythmias and 12 of 14 with ventricular tachycardia were controlled with amiodarone. Although side effects were common, only one patient was removed from treatment due to pulmonary fibrosis. We conclude that amiodarone is an effective antiarrhythmic drug for refractory ventricular and supraventricular arrhythmias.
胺碘酮用于治疗21例室上性或室性心律失常患者,这些患者单独或联合使用传统抗心律失常药物均无效。7例室上性心律失常患者中有6例,14例室性心动过速患者中有12例使用胺碘酮后病情得到控制。虽然副作用很常见,但只有1例患者因肺纤维化而停止治疗。我们得出结论,胺碘酮是治疗难治性室性和室上性心律失常的有效抗心律失常药物。