与菁染料共轭的堿基结合配体用于 DNA 双链体和 DNA-RNA 杂合体中孤儿碱基的“关-开”荧光传感。
Abasic site-binding ligands conjugated with cyanine dyes for "off-on" fluorescence sensing of orphan nucleobases in DNA duplexes and DNA-RNA hybrids.
机构信息
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
出版信息
Chem Commun (Camb). 2014 Jan 18;50(5):515-7. doi: 10.1039/c3cc47717g. Epub 2013 Nov 19.
PMID:24247159
Abstract
A series of abasic site-binding ligands conjugated with cyanine dyes have been developed for "off-on" fluorescence sensing of an orphan nucleobase in DNA duplexes and DNA-RNA hybrids.
摘要
一系列与菁染料缀合的碱基结合配体已被开发用于 DNA 双链体和 DNA-RNA 杂合体中孤儿碱基的“关闭-开启”荧光传感。
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