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心因性步态障碍:一项为期一年随访的物理康复随机对照试验。

Psychogenic gait disorder: a randomized controlled trial of physical rehabilitation with one-year follow-up.

机构信息

Vestfold Hospital Trust, Clinic physical medicine and rehabilitation, NO-3101 Tønsberg, Norway.

出版信息

J Rehabil Med. 2014 Feb;46(2):181-7. doi: 10.2340/16501977-1246.

Abstract

OBJECTIVE

Psychogenic gait disorder, defined as loss of ability to walk without neurological aetiologies, has poor rehabilitation options that are well documented. Left untreated these patients have substantial and long-lasting dysfunction. The present study examined the effect of a 3-week inpatient rehabilitation programme compared with a waiting list control condition, and whether eventual gains were maintained at 1-month and 1-year follow-up.

DESIGN

A cross-over design evaluated the effect of treatment, and a carry-over effect was considered as a long-lasting treatment effect. Treatment consisted of adapted physical activity within a cognitive behavioural framework, and focused on offering an alternative explanation of symptoms, positively reinforcing normal gait and not reinforcing dysfunction.

PATIENTS

A total of 60 patients were recruited from neurological departments and were randomly assigned to immediate treatment (intervention) or treatment after 4 weeks (controls).

RESULTS

Cross-over design revealed that the mean difference between treatment vs no treatment was 8.4 Functional Independence Measure units (p < 0.001, 95% confidence interval 5.2-11.7), and 6.9 Functional Mobility Scale units (p < 0.001, 95% confidence interval 5.5-8.3). Patients significantly improved their ability to walk and their quality of life after inpatient rehabilitation compared with the untreated control group. The improvements in gait were sustained at 1-month and 1-year follow-up.

CONCLUSION

Substantial and lasting improvement can be achieved by inpatient rehabilitation of patients with psychogenic gait, and the gains are maintained during follow-up.

摘要

目的

心因性步态障碍定义为无神经病因导致的行走能力丧失,其康复选择有限,这一点已有充分记录。如果不进行治疗,这些患者会出现严重且持久的功能障碍。本研究检查了为期 3 周的住院康复计划与等待名单对照条件的效果,以及最终的改善是否在 1 个月和 1 年随访时得以维持。

设计

交叉设计评估了治疗的效果,并考虑了治疗的延续效应,即长期治疗效果。治疗包括认知行为框架内的适应性身体活动,重点是提供对症状的替代解释,积极强化正常步态,不强化功能障碍。

患者

共有 60 名患者从神经科招募而来,并被随机分配接受立即治疗(干预组)或 4 周后治疗(对照组)。

结果

交叉设计显示,治疗与无治疗之间的平均差异为 8.4 个功能独立性测量单位(p<0.001,95%置信区间 5.2-11.7)和 6.9 个功能移动性量表单位(p<0.001,95%置信区间 5.5-8.3)。与未治疗的对照组相比,住院康复后的患者在行走能力和生活质量方面均有显著改善。步态的改善在 1 个月和 1 年随访时得以维持。

结论

通过对心因性步态障碍患者进行住院康复治疗,可以实现显著且持久的改善,并且在随访期间保持疗效。

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