Santos-Sacchi J
Hear Res. 1986;21(3):205-11. doi: 10.1016/0378-5955(86)90219-4.
Electrical coupling in an in vitro preparation of the organ of Corti was evaluated during changes in temperature of the bathing media. The effect of cooling the organ from 35 +/- 2 degrees C to 17 +/- 3 degrees C is to reduce membrane potentials, increase input resistance and decrease coupling ratios. Decreases in coupling ratios ranging from 15 to 75% have been observed. The effects are reversible upon warming. Membrane potentials are very susceptible to depolarization caused by cooling. The reduction in coupling is not due to depolarization nor is it dependent upon extracellular Ca2+. It is conceivable, however, that intracellular stores of Ca2+ are released or that intracellular pH is altered.
在体外制备的柯蒂氏器中，研究了浴液温度变化期间的电耦合情况。将柯蒂氏器从35±2℃冷却至17±3℃的作用是降低膜电位、增加输入电阻并降低耦合比。已观察到耦合比下降幅度在15%至75%之间。这些效应在升温时是可逆的。膜电位对冷却引起的去极化非常敏感。耦合的降低既不是由于去极化，也不依赖于细胞外Ca2+。然而，可以想象，细胞内Ca2+储存被释放或细胞内pH发生了改变。
