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小剂量琥珀酰胆碱对辅助喉罩置入效果的评估。

Assessment of Mini-dose Succinylcholine Effect on FacilitatingLaryngeal Mask Airway Insertion.

作者信息

Aghamohammadi Dawood, Eydi Mahmood, Hosseinzadeh Hamzeh, Amiri Rahimi Maryam, Golzari Samad Ej

机构信息

Department of Anesthesiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Cardiovasc Thorac Res. 2013;5(1):17-21. doi: 10.5681/jcvtr.2013.004. Epub 2013 Mar 17.

DOI:10.5681/jcvtr.2013.004
PMID:24251004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3825375/
Abstract

INTRODUCTION

Laryngeal Mask Airway (LMA) has gained wide acceptance for routine airway management and with increasing emphasis on day care surgery it is widely used. The aim of this study was to assess the effects of mini dose succinylcholine (0.1mg/kg) with semi-inflated cuff on facilitation of laryngeal mask airway insertion in order to achieve more satisfaction yet less complications .

METHODS

In a randomized double-blinded study, sixty ASA 1, 2 and 3 patients aged 20-60 years scheduled for urologic surgical procedures were included. Thirty patients received succinylcholine (Group S), and thirty received 0.9% sodium choride as a placebo (Group C).

RESULTS

Coughing occured in 33.3% of patients in the control group and there was no incidence in succ group (P=0.002). Head or limb movement occurred in 70% of the patients in the control group vs. 10% in succ group (P<0.001). Laryngospasm occurred in 36.6 % of the patients in the control group but there was no incidence in succ group (P=0.004). Additional propofol was required in 53% of the patients in control group vs. 10% for succ group (P=0.001). Ease of insertion and first successfull attempt of LMA were achieved in 93.3% and 90% of the patients respectively in group S (P<0.05). Myalgia and sore throat occurred in 66.7 % of patients in the group C in comparison with 33.3% in group S (P=0.06).

CONCLUSION

The combination of propofol with mini dose succinylcholine, provided a significantly better method for LMA insertion, while reduced propofol doses were needed and number of attempts decreased.

摘要

引言

喉罩气道(LMA)已被广泛接受用于常规气道管理,并且随着日间手术越来越受重视,其应用也越来越广泛。本研究的目的是评估小剂量琥珀胆碱(0.1mg/kg)联合半充气袖套对促进喉罩气道插入的效果,以期获得更高的满意度且减少并发症。

方法

在一项随机双盲研究中,纳入了60例年龄在20至60岁、计划接受泌尿外科手术的ASA 1、2和3级患者。30例患者接受琥珀胆碱(S组),30例患者接受0.9%氯化钠作为安慰剂(C组)。

结果

对照组33.3%的患者出现咳嗽,琥珀胆碱组未发生(P = 0.002)。对照组70%的患者出现头部或肢体移动,而琥珀胆碱组为10%(P < 0.001)。对照组36.6%的患者发生喉痉挛,琥珀胆碱组未发生(P = 0.004)。对照组53%的患者需要追加丙泊酚,而琥珀胆碱组为10%(P = 0.001)。S组分别有93.3%和90%的患者成功插入喉罩且首次尝试成功(P < 0.05)。C组66.7%的患者出现肌痛和咽痛,而S组为33.3%(P = 0.06)。

结论

丙泊酚与小剂量琥珀胆碱联合使用,为喉罩插入提供了一种明显更好的方法,同时所需丙泊酚剂量减少,尝试次数也减少。