Datta Saumik, Arora Rakesh, Chitra S, Chakraborty Partha, Baidya Arjun, Biswas Dibakar, Ghosh Sujoy
Department of Endocrinology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S333-4. doi: 10.4103/2230-8210.119633.
A 42-year-old lady, a known diabetic presented with generalized body ache, severe burning sensation over her lower limbs, loss of weight (approximately 8 kg), loss of appetite, nausea, frequent vomiting, and altered bowel habits without history of fever or pain abdomen. Symmetrical wasting was noted in all limbs with bilateral proximal muscle weakness, particularly of lower limbs. Ankle jerks were absent with symmetrically decreased reflexes. nerve conduction velocity (NCV) revealed symmetrical distal axonal and demyelinating type of sensorimotor polyneuropathy. Hematological and gastrointestinal (GI) malignancy were excluded. Patient responded to antidepressants.
一位42岁的已知糖尿病女性患者，出现全身疼痛、下肢严重烧灼感、体重减轻（约8千克）、食欲不振、恶心、频繁呕吐以及排便习惯改变，无发热或腹痛病史。所有肢体均出现对称性消瘦，伴有双侧近端肌肉无力，尤其是下肢。双侧跟腱反射消失，反射对称减弱。神经传导速度（NCV）显示为对称性远端轴索性和脱髓鞘性感觉运动性多发性神经病。排除血液系统和胃肠道（GI）恶性肿瘤。患者对抗抑郁药有反应。
