Malik Mohd Mustufa, Jindal Sushil, Bansal Shaifali, Saxena Vivek, Shukla Uma Shankar
Department of Medicine, People's College of Medical Sciences and Research Centre, Bhanpur, Bhopal, Madhya Pradesh, India.
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S340-1. doi: 10.4103/2230-8210.119641.
The primary objective of this study is to find out if testing ankle reflex (AR) alone is an effective screening tool for diabetic peripheral neuropathy and the secondary objective of this study is to compare its sensitivity and specificity with biothesiometer vibration perception threshold (VPT), which is the gold standard.
A total of 450 patients with diabetes mellitus attending endocrine out-patient department from year 2012 January to 2013 July were included in this study. All patients underwent clinical assessment of AR compared with VPT by biothesiometer.
AR is sensitive (81.09%) specific (81.679%) with diagnostic accuracy of (81.22%) and agreement between biothesiometer and AR is significant (κ = 0.538 P < 0.0001).
AR is at par the gold standard that is biothesiometer VPT.
本研究的主要目的是确定单独检测踝反射（AR）是否为糖尿病周围神经病变的有效筛查工具，次要目的是将其敏感性和特异性与作为金标准的生物感觉阈值测量仪振动觉阈值（VPT）进行比较。
本研究纳入了2012年1月至2013年7月在内分泌门诊就诊的450例糖尿病患者。所有患者均接受了AR的临床评估，并通过生物感觉阈值测量仪与VPT进行比较。
AR的敏感性为81.09%，特异性为81.679%，诊断准确性为81.22%，生物感觉阈值测量仪与AR之间的一致性显著（κ = 0.538，P < 0.0001）。
AR与作为金标准的生物感觉阈值测量仪VPT相当。
