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肾性佝偻病——实用方法

Renal rickets-practical approach.

作者信息

Sahay Manisha, Sahay Rakesh

机构信息

Department of Nephrology, Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, Haryana, India ; Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, Haryana, India.

出版信息

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S35-44. doi: 10.4103/2230-8210.119503.

DOI:10.4103/2230-8210.119503
PMID:24251212
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3830358/
Abstract

Rickets/osteomalacia is an important problem in a tropical country. Many cases are due to poor vitamin D intake or calcium deficient diets and can be corrected by administration of calcium and vitamin D. However, some cases are refractory to vitamin D therapy and are related to renal defects. These include rickets of renal tubular acidosis (RTA), hypophosphatemic rickets, and vitamin D dependent rickets (VDDR). The latter is due to impaired action of 1α-hydroxylase in renal tubule. These varieties need proper diagnosis and specific treatment.

摘要

佝偻病/骨软化症在热带国家是一个重要问题。许多病例是由于维生素D摄入不足或饮食中钙缺乏所致，通过补充钙和维生素D可以纠正。然而，有些病例对维生素D治疗无效，与肾脏缺陷有关。这些包括肾小管酸中毒（RTA）佝偻病、低磷血症性佝偻病和维生素D依赖性佝偻病（VDDR）。后者是由于肾小管中1α-羟化酶的作用受损。这些类型需要正确诊断和特殊治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32c5/3830358/8ed1706b870d/IJEM-17-35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32c5/3830358/8ed1706b870d/IJEM-17-35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32c5/3830358/8ed1706b870d/IJEM-17-35-g001.jpg

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本文引用的文献

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Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia.成骨细胞调节磷酸盐稳态和矿化作用是遗传性佝偻病和骨软化症病理生理学的基础。
Bone. 2013 Jun;54(2):213-21. doi: 10.1016/j.bone.2013.01.046. Epub 2013 Feb 9.
2
Tumor localization and biochemical response to cure in tumor-induced osteomalacia.肿瘤所致骨软化症中的肿瘤定位和生化反应。
J Bone Miner Res. 2013 Jun;28(6):1386-98. doi: 10.1002/jbmr.1881.
3
Improving diagnosis of tumor-induced osteomalacia with Gallium-68 DOTATATE PET/CT.
Ann Afr Med. 2023 Jan-Mar;22(1):128-130. doi: 10.4103/aam.aam_198_21.
4
The genetic and epigenetic contributions to the development of nutritional rickets.遗传和表观遗传因素对营养性佝偻病的发生发展的影响。
Front Endocrinol (Lausanne). 2022 Dec 22;13:1059034. doi: 10.3389/fendo.2022.1059034. eCollection 2022.
5
Rickets in Children: An Update.儿童佝偻病：最新进展
Biomedicines. 2021 Jun 27;9(7):738. doi: 10.3390/biomedicines9070738.
6
Shedding light on vitamin D: the shared mechanistic and pathophysiological role between hypovitaminosis D and COVID-19 risk factors and complications.揭示维生素 D 的奥秘：维生素 D 缺乏症与 COVID-19 风险因素和并发症之间的共同机制和病理生理学作用。
Inflammopharmacology. 2021 Aug;29(4):1017-1031. doi: 10.1007/s10787-021-00835-6. Epub 2021 Jun 29.
7
Clinical and genetic analysis of two Chinese families with vitamin D-dependent rickets type IA and follow-up.两例维生素 D 依赖性佝偻病 IA 型家系的临床与遗传学分析及随访
Orphanet J Rare Dis. 2020 Oct 1;15(1):273. doi: 10.1186/s13023-020-01558-7.
8
An Overview of Rickets in Children.儿童佝偻病概述
Kidney Int Rep. 2020 Apr 11;5(7):980-990. doi: 10.1016/j.ekir.2020.03.025. eCollection 2020 Jul.
9
Nutritional hypophosphatemic rickets secondary to Neocate® use.因使用 Neocate®导致的营养性低磷抗维生素 D 佝偻病。
Osteoporos Int. 2019 Sep;30(9):1887-1891. doi: 10.1007/s00198-019-04836-8. Epub 2019 May 29.
10
An 18-month-old boy with growth failure and gross motor skill regression.一名18个月大的男童，伴有生长发育迟缓及粗大运动技能倒退。
Paediatr Child Health. 2017 Oct;22(7):363-364. doi: 10.1093/pch/pxx107. Epub 2017 Sep 25.
用镓-68 DOTATATE PET/CT 提高肿瘤性骨软化症的诊断。
J Clin Endocrinol Metab. 2013 Feb;98(2):687-94. doi: 10.1210/jc.2012-3642. Epub 2013 Jan 7.
4
Rickets-vitamin D deficiency and dependency.佝偻病——维生素D缺乏与依赖
Indian J Endocrinol Metab. 2012 Mar;16(2):164-76. doi: 10.4103/2230-8210.93732.
5
The importance of whole body imaging in tumor-induced osteomalacia.全身成像在肿瘤诱导性骨软化症中的重要性。
J Clin Endocrinol Metab. 2011 Dec;96(12):3599-600. doi: 10.1210/jc.2011-1757.
6
Two new unrelated cases of hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from the same novel nonsense mutation in the vitamin D receptor gene.两例新的非亲缘性遗传性1,25 - 二羟维生素D抵抗性佝偻病伴脱发病例，病因是维生素D受体基因中相同的新型无义突变。
J Pediatr Endocrinol Metab. 2010 Aug;23(8):843-50. doi: 10.1515/jpem.2010.136.
7
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Nat Rev Nephrol. 2010 Nov;6(11):657-65. doi: 10.1038/nrneph.2010.121. Epub 2010 Oct 5.
8
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Ann N Y Acad Sci. 2010 Mar;1192:190-200. doi: 10.1111/j.1749-6632.2010.05387.x.
10
Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from a novel missense mutation in the DNA-binding domain of the vitamin D receptor.遗传性 1,25-二羟维生素 D 抵抗性佝偻病伴脱发，其病因是维生素 D 受体 DNA 结合域的新型错义突变。
Mol Genet Metab. 2010 Jan;99(1):72-9. doi: 10.1016/j.ymgme.2009.09.004.