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一例伴横纹肌溶解的皮肌炎,经静脉注射免疫球蛋白救治。

A case of dermatomyositis with rhabdomyolysis, rescued by intravenous immunoglobulin.

作者信息

Mizoguchi Fumitaka, Takada Kazuki, Ishikawa Kinya, Mizusawa Hidehiro, Kohsaka Hitoshi, Miyasaka Nobuyuki

机构信息

Department of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Tokyo , Japan.

出版信息

Mod Rheumatol. 2015 Jul;25(4):646-8. doi: 10.3109/14397595.2013.843753. Epub 2013 Nov 5.

Abstract

We describe a case of severe dermatomyositis (DM) complicated by rhabdomyolysis, acute tubular necrosis, and hemophagocytosis. The case failed to respond to corticosteroids, but showed rapid and significant improvement after the addition of intravenous immunoglobulin (IVIG). While the prognosis of DM is poor when it is complicated by rhabdomyolysis, the early administration of IVIG has the potential to be the cornerstone of its management.

摘要

我们描述了一例严重皮肌炎(DM)并发横纹肌溶解症、急性肾小管坏死和噬血细胞综合征的病例。该病例对皮质类固醇治疗无效,但在加用静脉注射免疫球蛋白(IVIG)后迅速且显著改善。虽然DM并发横纹肌溶解症时预后较差,但早期给予IVIG有可能成为其治疗的基石。

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