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颌骨血管外皮细胞瘤

Haemangiopericytoma of the jaw.

作者信息

Wushou Alimujiang, Bai Xiu Feng, Qi Hong, Xu Zhe, Zheng Jun, Li Gang

机构信息

Department of Oncology, Cancer Hospital/Cancer Institute, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oral and Maxillofacial-Head and Neck Oncology, Stomatology Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, China.

Department of Oral and Maxillofacial-Head and Neck Oncology, Stomatology Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, China.

出版信息

J Craniomaxillofac Surg. 2014 Jul;42(5):689-94. doi: 10.1016/j.jcms.2013.09.016. Epub 2013 Oct 16.

Abstract

Haemangiopericytoma (HPC) is a vascular tumour which originates in the pericytes of vessels and therefore it may occur at any site, but it is very uncommon in the jaw. From January 2000 to December 2011, a retrospective analysis of nine consecutive patients with HPCJ was performed. There were five patients with a primary tumour and four patients with a recurrent tumour. Of the nine patients, eight were male and one female. Their ages ranged from 23 years to 51 years, with a median age of 38 years. The tumours were located in the mandible in six patients and in maxilla in three cases. The median course of disease was 7.6 months (range 2-12 months). All patients underwent surgery. Two patients had postoperative adjuvant radiotherapy, and two cases were given postoperative adjuvant chemotherapy. The median follow-up period was 49 months (10-101 months). One patient suffered from lumbar metastasis, while another case had metastasis at local and multiple distant sites, and eventually died. There was no local recurrence or metastasis in other seven cases. HPCJ are rare and the clinical characteristics are not specific. The first choice of treatment is radical surgery. Adjuvant radiotherapy may be effective to improve the prognosis of HPCJ.

摘要

血管外皮细胞瘤(HPC)是一种起源于血管周细胞的血管肿瘤,因此可发生于任何部位,但在颌骨中非常罕见。对2000年1月至2011年12月期间连续9例颌骨血管外皮细胞瘤患者进行回顾性分析。其中5例为原发性肿瘤,4例为复发性肿瘤。9例患者中,8例为男性,1例为女性。年龄范围为23岁至51岁,中位年龄为38岁。肿瘤位于下颌骨6例,上颌骨3例。疾病的中位病程为7.6个月(范围2 - 12个月)。所有患者均接受了手术治疗。2例患者术后接受了辅助放疗,2例患者接受了术后辅助化疗。中位随访期为49个月(10 - 101个月)。1例患者发生腰椎转移,另1例患者局部及多处远处转移,最终死亡。其他7例无局部复发或转移。颌骨血管外皮细胞瘤罕见,临床特征不具特异性。治疗的首选是根治性手术。辅助放疗可能对改善颌骨血管外皮细胞瘤的预后有效。

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