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Pharmacokinetics and dosage individualization of ganciclovir and valganciclovir in an infant with nephrotic syndrome associated with cytomegalovirus infection.

作者信息

Zhang Bo, Fila Marc, Fakhoury May, Baudouin Véronique, Deschênes Georges, Jacqz-Aigrain Evelyne, Zhao Wei

机构信息

Emergency Department, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

J Antimicrob Chemother. 2014 Apr;69(4):1150-1. doi: 10.1093/jac/dkt472. Epub 2013 Nov 19.

DOI:10.1093/jac/dkt472
PMID:24252753
Abstract
摘要

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1
Pharmacokinetics and dosage individualization of ganciclovir and valganciclovir in an infant with nephrotic syndrome associated with cytomegalovirus infection.一名患有与巨细胞病毒感染相关的肾病综合征婴儿的更昔洛韦和缬更昔洛韦的药代动力学及剂量个体化
J Antimicrob Chemother. 2014 Apr;69(4):1150-1. doi: 10.1093/jac/dkt472. Epub 2013 Nov 19.
2
Artesunate is ineffective in controlling valganciclovir-resistant cytomegalovirus infection.青蒿琥酯在控制缬更昔洛韦耐药的巨细胞病毒感染方面无效。
Clin Infect Dis. 2011 Jan 15;52(2):279. doi: 10.1093/cid/ciq050.
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Pharmacokinetics of valganciclovir and ganciclovir in renal impairment.缬更昔洛韦和更昔洛韦在肾功能损害患者中的药代动力学。
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[Disease by CMV resistant to Ganciclovir. Should plasma valganciclovir levels be monitored in high risk patients?].[巨细胞病毒（CMV）感染的疾病对更昔洛韦耐药。高危患者是否应监测缬更昔洛韦血浆水平？]
Nefrologia. 2009;29(2):180-1. doi: 10.3265/Nefrologia.2009.29.2.4889.en.full.
5
Preemptive valganciclovir for cytomegalovirus infection in hematological patients.抢先使用缬更昔洛韦治疗血液病患者的巨细胞病毒感染
Transpl Infect Dis. 2008 Oct;10(5):375-6. doi: 10.1111/j.1399-3062.2008.00306.x.
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Clinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir in children with cytomegalovirus infection.更昔洛韦和缬更昔洛韦在儿童巨细胞病毒感染中的临床药代动力学和药效学。
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Oral valganciclovir treatment in newborns with symptomatic congenital cytomegalovirus infection.口服缬更昔洛韦治疗有症状的先天性巨细胞病毒感染的新生儿。
Eur J Clin Microbiol Infect Dis. 2009 Dec;28(12):1465-70. doi: 10.1007/s10096-009-0806-5. Epub 2009 Sep 11.
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Ganciclovir concentrations in the cerebral extracellular space after valganciclovir treatment; a case study.缬更昔洛韦治疗后大脑细胞外间隙中的更昔洛韦浓度；一项病例研究。
BMJ Case Rep. 2015 Dec 15;2015:bcr2014207694. doi: 10.1136/bcr-2014-207694.
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Sequential treatment of cytomegalovirus infection or disease with a short course of intravenous ganciclovir followed by oral valganciclovir: efficacy, safety, and pharmacokinetics.采用短疗程静脉注射更昔洛韦继以口服缬更昔洛韦序贯治疗巨细胞病毒感染或疾病：疗效、安全性及药代动力学
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[Valganciclovir. Oral treatment of Cytomegalovirus infections].[缬更昔洛韦。巨细胞病毒感染的口服治疗]
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引用本文的文献

1
Renal Involvement in Congenital Cytomegalovirus Infection: A Systematic Review.先天性巨细胞病毒感染中的肾脏受累：一项系统评价。
Microorganisms. 2021 Jun 15;9(6):1304. doi: 10.3390/microorganisms9061304.
2
Case Report: CMV-Associated Congenital Nephrotic Syndrome.病例报告：巨细胞病毒相关先天性肾病综合征
Front Pediatr. 2020 Nov 27;8:580178. doi: 10.3389/fped.2020.580178. eCollection 2020.
3
Pediatric Dosing of Ganciclovir and Valganciclovir: How Model-Based Simulations Can Prevent Underexposure and Potential Treatment Failure.
更昔洛韦和缬更昔洛韦在儿科的给药剂量：基于模型的模拟如何预防剂量不足和潜在的治疗失败。
CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):167-176. doi: 10.1002/psp4.12363. Epub 2018 Dec 18.