Shafiq Ali, Nguyen Phuc, Hudson Michael P, Rabbani Bobak
Henry Ford Hospital, Detroit, Michigan, USA.
BMJ Case Rep. 2013 Nov 19;2013:bcr2013202001. doi: 10.1136/bcr-2013-202001.
Paragangliomas and pheochromocytomas are catecholamine-secreting tumours which if remain undiagnosed may cause severe morbidity and mortality. In rare circumstances these tumours can cause left ventricular (LV) thrombi to form by inducing cardiomyopathy and subsequent embolic complications. After a thorough literature review, six previous cases were found that presented the formation of an LV thrombus in the setting of a pheochromocytoma or paraganglioma. A majority of these cases were associated with significant wall motion abnormalities and their cardiac ejection fraction (EF) was compromised. This is a rare case of a patient developing LV thrombi in the setting of a paraganglioma with normal cardiac EF. We present this case to compare the similarities and differences of our case with previously reported cases and emphasise the importance of suspecting these LV thrombi in patients with these neuroendocrine tumours.
副神经节瘤和嗜铬细胞瘤是分泌儿茶酚胺的肿瘤，如果未被诊断出来，可能会导致严重的发病率和死亡率。在罕见情况下，这些肿瘤可通过诱发心肌病及随后的栓塞并发症，导致左心室（LV）血栓形成。经过全面的文献回顾，发现了6例先前的病例，这些病例均出现了嗜铬细胞瘤或副神经节瘤患者左心室血栓形成。这些病例中的大多数都伴有明显的室壁运动异常，且其心脏射血分数（EF）受损。这是1例罕见的副神经节瘤患者出现左心室血栓形成且心脏EF正常的病例。我们展示此病例，以比较我们的病例与先前报道病例的异同，并强调在这些神经内分泌肿瘤患者中怀疑存在这些左心室血栓的重要性。
