Cátedra de Química Biológica, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, 5016, Córdoba, Argentina.
Theor Appl Genet. 1985 Aug;70(5):569-72. doi: 10.1007/BF00305992.
Six population samples of the South American cricetid rodent Akodon dolores were collected at the same site at six-month intervals over a three year period. Changes in density were detected. Seven out of 18 loci analyzed by means of starch gel electrophoresis were polymorphic. Only two of these loci (Est-4 and G6pdh) showed statistically significant variation in allele frequencies following a seasonal pattern. There was no correlation between allele frequencies and population density. When animals were grouped into two classes according to body weight, a clear difference in allele distribution at the Est-4 and G6pdh loci was observed between individuals 39 g or less and those heavier than 39 g. As the first group comprises predominantly younger animals, the data indicate that changes in the age-structure of population, rather than density variations, are responsible for the cyclic pattern of allele frequencies fluctuations.
在三年的时间里，每隔六个月在同一地点采集了 6 个人口样本的南美仓鼠属啮齿动物 Akodon dolores。检测到密度变化。通过淀粉凝胶电泳分析的 18 个基因座中的 7 个具有多态性。只有这两个基因座（Est-4 和 G6pdh）在遵循季节性模式的等位基因频率方面表现出统计学上的显著差异。等位基因频率与种群密度之间没有相关性。当根据体重将动物分为两类时，在 Est-4 和 G6pdh 基因座上的等位基因分布存在明显差异，体重在 39 克或以下的个体与体重超过 39 克的个体之间存在差异。由于第一组主要由较年轻的动物组成，数据表明，种群的年龄结构变化而不是密度变化是导致等位基因频率波动周期性模式的原因。
