The deciphered genome of Mesobuthus martensii uncovers the resistance mysteries of scorpion to its own venom and toxins at the ion channel level.
作者信息
Andreotti Nicolas, Sabatier Jean-Marc
机构信息
Laboratoire INSERM UMR 1097, Université d'Aix-Marseille, 163, Avenue de Luminy, Case 939, TPR2 INSERM, 13288 Marseille Cedex 09, France.
出版信息
Toxins (Basel). 2013 Nov 18;5(11):2209-11. doi: 10.3390/toxins5112209.
Abstract
摘要
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The deciphered genome of Mesobuthus martensii uncovers the resistance mysteries of scorpion to its own venom and toxins at the ion channel level.东亚钳蝎的破译基因组在离子通道水平上揭示了蝎子对自身毒液和毒素的抗性奥秘。
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本文引用的文献
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The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods.马氏正钳蝎基因组揭示节肢动物的独特适应模式。
Nat Commun. 2013;4:2602. doi: 10.1038/ncomms3602.
2
Epidemiology of scorpionism: a global appraisal.蝎蜇伤流行病学：全球评估
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Molecular cloning and sequencing of two 'short chain' and two 'long chain' K(+) channel-blocking peptides from the Chinese scorpion Buthus martensii Karsch.从中华蝎东亚钳蝎中克隆和测序两种“短链”和两种“长链”钾离子通道阻断肽
FEBS Lett. 1999 Sep 3;457(3):509-14. doi: 10.1016/s0014-5793(99)01101-1.
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Clinical manifestations and management of scorpion envenomation.蝎子蜇伤的临床表现及处理
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The myth of scorpion suicide: are scorpions insensitive to their own venom?蝎子自杀的神话：蝎子对自身毒液不敏感吗？
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A human intermediate conductance calcium-activated potassium channel.一种人类中间电导钙激活钾通道。
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Charybdotoxin block of Shaker K+ channels suggests that different types of K+ channels share common structural features.沙蚕毒素对Shaker钾通道的阻断表明，不同类型的钾通道具有共同的结构特征。
Neuron. 1988 Dec;1(10):997-1001. doi: 10.1016/0896-6273(88)90156-0.
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