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古巴哈瓦那的妇女中的艾滋病毒/艾滋病:1986-2011 年。

HIV/AIDS among women in Havana, Cuba: 1986-2011.

机构信息

Enrique Cabrera General Teaching Hospital, Medical University of Havana, Cuba.

出版信息

MEDICC Rev. 2013 Oct;15(4):29-35. doi: 10.37757/MR2013V15.N4.8.

DOI:10.37757/MR2013V15.N4.8
PMID:24253348
Abstract

INTRODUCTION

Women are being diagnosed with HIV infection in increasing numbers, and now account for 50% of cases worldwide. In Cuba, HIV is more frequent in men, but in recent years, a growing number of women have been diagnosed.

OBJECTIVE

Describe patterns of HIV among women in Havana, Cuba, 1986-2011.

METHODS

Descriptive study of women with HIV aged >14 years, residents of Havana, Cuba, who were diagnosed with HIV from 1 January 1986 through 31 December 2011. Information was obtained from the limited-access HIV/AIDS database of Cuba's Ministry of Public Health. Data were studied from all reported cases, a total of 1274 women. Variables selected were age at diagnosis, education, municipality of residence, screening group, year of HIV diagnosis, late presentation, AIDS-defining condition, year of diagnosis as AIDS case, vital status at the end of 2011, and year of death (if applicable). Incidence of HIV and AIDS, cumulative incidence by municipality of residence, and case fatality rates were calculated.

RESULTS

Those aged 20-29 years were most affected by HIV. Almost half (46.7%) the women had completed middle school, and a further 35.4% had completed high school or middle-level technical studies. HIV incidence began to increase more steeply starting in 1998, as did AIDS incidence by year of diagnosis, though to a lesser extent. Central Havana and Old Havana municipalities had the highest cumulative incidence. Late presentation was seen in 7.4% of cases; mean age of those diagnosed late was 38.9 years. Wasting syndrome and Pneumocystis jirovecii pneumonia were the most frequent AIDS-defining conditions. Case fatality rates started to decline in 1998.

CONCLUSIONS

HIV infection in women is occurring in a predominantly young, relatively well-educated population. Increasing rates of HIV and AIDS in the past decade are a warning sign of the possible expansion of HIV infection in women, even though mortality is declining.

摘要

简介

感染 HIV 的女性人数正在不断增加,目前占全球病例的 50%。在古巴,HIV 感染多见于男性,但近年来,被诊断出患有 HIV 的女性人数不断增加。

目的

描述 1986 年至 2011 年期间,在古巴哈瓦那感染 HIV 的女性的 HIV 感染模式。

方法

对 1986 年 1 月 1 日至 2011 年 12 月 31 日期间,在古巴哈瓦那居住并被诊断为 HIV 阳性的年龄超过 14 岁的女性进行 HIV 感染者的描述性研究。从古巴卫生部的 HIV/AIDS 数据库中获取信息。对所有报告的病例进行研究,共涉及 1274 名女性。选择的变量包括诊断时的年龄、教育程度、居住地的自治市、筛查组、HIV 诊断年份、晚期表现、艾滋病定义条件、诊断为艾滋病病例的年份、2011 年底的生存状态以及死亡年份(如适用)。计算 HIV 和艾滋病的发病率、按居住地自治市计算的累积发病率和病死率。

结果

20-29 岁的女性受 HIV 的影响最大。将近一半(46.7%)的女性完成了中学学业,另有 35.4%的女性完成了高中或中级技术研究。1998 年开始,HIV 发病率和艾滋病诊断年份的发病率开始急剧上升,尽管幅度较小。哈瓦那中心和老哈瓦那自治市的累积发病率最高。7.4%的病例为晚期表现;诊断为晚期的患者平均年龄为 38.9 岁。消瘦综合征和卡氏肺孢子虫肺炎是最常见的艾滋病定义条件。病死率自 1998 年开始下降。

结论

HIV 感染在女性中主要发生在年轻、受教育程度相对较高的人群中。过去十年 HIV 和艾滋病发病率的上升是 HIV 感染在女性中可能扩大的警告信号,尽管死亡率正在下降。

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