Departments of *Orthopedics and †Nephrology, the People's Hospital of Three Gorges University, the First People's Hospital of Yichang, Yichang, Hubei Province, China.
Spine (Phila Pa 1976). 2014 Feb 1;39(3):256-62. doi: 10.1097/BRS.0000000000000115.
A comparative study.
The aims of this study were to: (1) evaluate Scoliosis Research Society (SRS)-22 questionnaire performance in normal adolescents without scoliosis to establish a normative baseline useful for evaluating the discriminate validity of the SRS-22 in primary adolescent scoliosis; and (2) investigate impact of age and sex on SRS-22 in an adolescent population unaffected by scoliosis.
The SRS-22 questionnaire is widely used to measure health-related quality of life of patients with spinal disease including scoliosis and lumbar spondylolisthesis. However, normal data, which are very important, when comparing patients and nonpatients, are few, little, and there are few studies about factors that may affect SRS questionnaire performance.
The adolescent population was from 14 schools located in 7 provinces. A total of 2008 adolescents (961 females, 1026 males, 21 unknown; mean age, 14.3 yr; range, 11-20) completed the simplified Chinese version of SRS-22 questionnaire and demographic questions. Surveys were stratified into 8 age-sex groups for analysis: male/female; 12 to 13.4, 13.5 to 14.9, 15 to 15.9, and more than 16 years of age. Post hoc testing and the Tukey least significant difference were used to compare differences between any 2 of the 4 age groups.
Self-image scores in males were higher than those in females (P < 0.01). Pain domain scores were significantly higher in males than those in females in the 13.5- to 14.9-year-old subgroup, whereas other subgroups showed no obvious differences. The function domain scores in males who were aged 15 to 15.9 years and those older than 16 years were significantly higher than those in females (P < 0.001). There were no statistically significant differences in mental health domain scores among age-sex subgroups, with the exception of the 13.5- to 14.9-year-old group.
This is the first study to characterize the sex and age influence on the SRS-22 scores in normal population. Age and sex have an important effect on SRS-22 scores, so when using the instrument to assess health-related quality of life of patients with scoliosis or other spinal disease, we should consider the differences in patients with different age and sex.
一项对比研究。
本研究的目的是：(1)评估无脊柱侧弯的正常青少年的 Scoliosis Research Society (SRS)-22 问卷表现，为原发性青少年脊柱侧弯的 SRS-22 提供有用的鉴别效度的基准；(2)研究年龄和性别对无脊柱侧弯青少年 SRS-22 问卷的影响。
SRS-22 问卷广泛用于评估脊柱疾病（包括脊柱侧凸和腰椎滑脱）患者的健康相关生活质量。然而，当比较患者和非患者时，非常重要的正常数据却很少，几乎没有，并且很少有研究涉及可能影响 SRS 问卷表现的因素。
青少年人群来自分布于 7 个省的 14 所学校。共有 2008 名青少年（961 名女性，1026 名男性，21 名未知；平均年龄 14.3 岁；范围 11-20 岁）完成了简化中文版 SRS-22 问卷和人口统计学问题的调查。调查按 8 个年龄性别组进行分层分析：男性/女性；12 至 13.4 岁、13.5 至 14.9 岁、15 至 15.9 岁及 16 岁以上。使用事后检验和 Tukey 最小显著差异法比较任意两个 4 个年龄组之间的差异。
男性的自我形象评分高于女性（P<0.01）。13.5 至 14.9 岁亚组中，男性的疼痛域评分明显高于女性，而其他亚组则无明显差异。15 至 15.9 岁和 16 岁以上男性的功能域评分明显高于女性（P<0.001）。除 13.5 至 14.9 岁年龄组外，年龄性别亚组的心理健康域评分无统计学差异。
这是首次研究正常人群中 SRS-22 评分的性别和年龄影响。年龄和性别对 SRS-22 评分有重要影响，因此在使用该工具评估脊柱侧凸或其他脊柱疾病患者的健康相关生活质量时，应考虑到不同年龄和性别的患者的差异。
3 级。
