急性肠系膜缺血的现代治疗。

Modern treatment of acute mesenteric ischaemia.

机构信息

Vascular Centre, Skåne University Hospital, Malmö, Sweden.

出版信息

Br J Surg. 2014 Jan;101(1):e100-8. doi: 10.1002/bjs.9330. Epub 2013 Nov 20.

Abstract

BACKGROUND

Diagnosis of acute mesenteric ischaemia in the early stages is now possible with modern computed tomography (CT), using intravenous contrast enhancement and imaging in the arterial and/or portal venous phase. The availability of CT around the clock means that more patients with acute mesenteric ischaemia may be treated with urgent intestinal revascularization.

METHODS

This was a review of modern treatment strategies for acute mesenteric ischaemia.

RESULTS

Endovascular therapy has become an important alternative, especially in patients with acute thrombotic superior mesenteric artery (SMA) occlusion, where the occlusive lesion can be recanalized either antegradely from the femoral or brachial artery, or retrogradely from an exposed SMA after laparotomy, and stented. Aspiration embolectomy, thrombolysis and open surgical embolectomy, followed by on-table angiography, are the treatment options for embolic SMA occlusion. Endovascular therapy may be an option in the few patients with mesenteric venous thrombosis who do not respond to anticoagulation therapy. Laparotomy is needed to evaluate the extent and severity of visceral organ ischaemia, which is treated according to the principles of damage control surgery.

CONCLUSION

Modern treatment of acute mesenteric ischaemia involves a specialized approach that considers surgical and, increasingly, endovascular options for best outcomes.

摘要

背景

现代计算机断层扫描(CT)技术可通过静脉内对比增强和动脉期及/或门静脉期成像来早期诊断急性肠系膜缺血。由于 CT 可随时使用,因此更多急性肠系膜缺血患者可能会接受紧急肠血运重建治疗。

方法

这是对急性肠系膜缺血现代治疗策略的回顾。

结果

血管内治疗已成为一种重要的替代方法,特别是在急性血栓性肠系膜上动脉(SMA)闭塞患者中,闭塞病变可以从股动脉或肱动脉顺行再通,也可以在剖腹手术后从暴露的 SMA 逆行再通并支架置入。抽吸血栓切除术、溶栓和开放手术血栓切除术,随后进行术中血管造影,是 SMA 栓塞的治疗选择。对于少数对抗凝治疗无反应的肠系膜静脉血栓形成患者,血管内治疗可能是一种选择。剖腹探查术用于评估内脏器官缺血的程度和严重程度,并根据损伤控制手术的原则进行治疗。

结论

急性肠系膜缺血的现代治疗涉及一种专门的方法,综合考虑手术和越来越多的血管内治疗选择,以获得最佳结果。

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