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经椎间孔硬膜外类固醇注射治疗硬膜外脂肪增多症所致腰骶部神经根性疼痛:病例系列及文献复习

Transforaminal epidural steroid injection in the treatment of lumbosacral radicular pain caused by epidural lipomatosis: a case series and review.

作者信息

McCormick Zack, Plastaras Christopher

机构信息

Department of PM&R, Rehabilitation Institute of Chicago, Northwestern University, Chicago, IL, USA.

Department of PM&R, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

J Back Musculoskelet Rehabil. 2014;27(2):181-90. doi: 10.3233/BMR-130434.

Abstract

BACKGROUND

Spinal epidural lipomatosis (SEL) can cause radicular pain due to spinal nerve root impingement. While SEL decompression surgery can provide symptom relief, these patients are often poor surgical candidates due to elevated BMI or immunosuppression. Transforaminal epidural steroid injection (TFESI) has been attempted as an alternative treatment for patients with SEL who are unable to tolerate conservative medical treatment. To date, only two such cases have been reported in the literature.

OBJECTIVES

We report three additional cases of radicular pain associated with SEL, review the current literature on this condition, and describe the risks and benefits of using TFESI to treat radicular pain due to SEL.

METHODS

We measured changes on the pain visual analogue scale (VAS) and pain disability index (PDI) from presentation to 1-5 weeks after treatment with sequential TFESIs.

RESULTS

Pain VAS scores improved by 50-75% and PDI scores improved 13-44 points.

CONCLUSIONS

This case series suggests that TFESI can provide modest short-term symptom relief of lumbosacral radicular pain and improvement in disability caused by SEL. Further study of non-operative management of SEL is warranted, given the high risk associated with surgery in this population.

摘要

背景

脊髓硬膜外脂肪增多症(SEL)可因脊神经根受压而导致神经根性疼痛。虽然SEL减压手术可缓解症状,但由于患者BMI升高或免疫抑制,这些患者往往不是手术的理想人选。对于无法耐受保守药物治疗的SEL患者,经椎间孔硬膜外类固醇注射(TFESI)已被尝试作为一种替代治疗方法。迄今为止,文献中仅报道了两例此类病例。

目的

我们报告另外三例与SEL相关的神经根性疼痛病例,回顾关于这种情况的现有文献,并描述使用TFESI治疗SEL所致神经根性疼痛的风险和益处。

方法

我们测量了从就诊到接受序贯TFESI治疗后1至5周期间疼痛视觉模拟量表(VAS)和疼痛残疾指数(PDI)的变化。

结果

疼痛VAS评分改善了50%至75%,PDI评分改善了13至44分。

结论

该病例系列表明,TFESI可在短期内适度缓解腰骶部神经根性疼痛,并改善SEL所致的残疾状况。鉴于该人群手术风险高,有必要对SEL的非手术治疗进行进一步研究。

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