Graduate Program in Nutritional Sciences, Health Sciences Center, NIESN-Interdisciplinary Center for Studies in Health and Nutrition, Federal University of Paraíba, Castelo Branco, João Pessoa, PB, 58059-900, Brazil,
Obes Surg. 2014 May;24(5):771-6. doi: 10.1007/s11695-013-1132-7.
To our knowledge, the frequency of serum chromium deficiency in patients awaiting bariatric surgery has not been determined. This study was designed to assess chromium concentration and its association with glycemic levels and lipid profile in patients prior to bariatric surgery.
This study recruited 73 candidates for bariatric surgery between March and September 2012. Their sociodemographic, anthropometric, and biochemical data were collected.
Of the 73 patients, 55 (75.3%) were women (75.34%). Mean patient age was 37.20 ± 9.92 years, and mean body mass index was 47.48 kg/m2 (range, 43.59 to 52.50 kg/m2). Chromium deficiency was observed in 64 patients (87.7%). Correlation analysis showed significant negative relationships between chromium concentration and BMI and zinc concentration and a significant positive relationship between chromium and glycated hemoglobin. Multiple linear regression analysis showed that serum chromium concentration was significantly associated with total cholesterol (β = 0.171, p = 0.048) and triglyceride (β = -0.181, p = 0.039) concentrations.
Serum chromium deficiency is frequent in candidates for bariatric surgery and is associated with total cholesterol and triglyceride concentrations. Early nutritional interventions are needed to reduce nutritional deficiencies and improve the lipid profile of these patients.
据我们所知，待行减重手术患者的血清铬缺乏频率尚未确定。本研究旨在评估铬浓度及其与减重手术前患者血糖水平和血脂谱的关系。
本研究于 2012 年 3 月至 9 月招募了 73 名拟行减重手术的患者。收集了他们的社会人口统计学、人体测量学和生化数据。
73 例患者中，55 例（75.3%）为女性（75.34%）。患者平均年龄为 37.20±9.92 岁，平均体重指数为 47.48kg/m2（范围为 43.59-52.50kg/m2）。64 例（87.7%）患者存在铬缺乏。相关性分析显示，铬浓度与 BMI 及锌浓度呈显著负相关，与糖化血红蛋白呈显著正相关。多元线性回归分析显示，血清铬浓度与总胆固醇（β=0.171，p=0.048）和甘油三酯（β=-0.181，p=0.039）浓度显著相关。
减重手术候选者中存在血清铬缺乏，且与总胆固醇和甘油三酯浓度有关。需要早期进行营养干预，以减少这些患者的营养缺乏并改善其血脂谱。
