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The effects of the anaphylatoxins C3a and C5a on isolated mast cells from rat and man.

作者信息

Jürgensen H, Behrendt H, Damerau B, Schmutzler W

出版信息

Agents Actions. 1986 Apr;18(1-2):153-4. doi: 10.1007/BF01988008.

Abstract

Of the complement peptides comprising anaphylatoxin activity, only C5a caused a very small (less than 1.5%) but statistically significant histamine release from isolated human adenoidal mast cells. C3a and the respective des-Arg-derivatives were found to be ineffective. In rat peritoneal mast cells, neither peptide caused histamine release.

摘要

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