Miremadi Seyed Reza, De Bruyn Hugo, Steyaert Harold, Princen Katrijn, Sabzevar Mehran M, Cosyn Jan
Department of Periodontology and Oral Implantology, Dental School, Faculty of Medicine and Health Sciences, University of Ghent, Ghent, Belgium.
J Clin Periodontol. 2014 Feb;41(2):164-71. doi: 10.1111/jcpe.12201.
To compare immediate surgery to scaling and root planing (SRP) in the treatment of advanced periodontal disease focusing on the prevalence of residual sites and cost-effectiveness (1); to evaluate the adjunctive effects of azithromycin in a second treatment phase (2).
Thirty-nine patients (18 males, 21 females; mean age: 54.6) received oral hygiene instructions and were randomly allocated to surgery (n = 19) or SRP (n = 20). Patients with residual pockets (≥6 mm) at 6 months received re-debridement of these sites and systemic azithromycin. Treatment groups were followed up to 12 months and evaluated in terms of clinical response parameters and cost-effectiveness. Chair-time was used to assess the financial impact of treatment.
Both treatment arms were equally effective in terms of clinical outcome demonstrating less than 1% residual pockets at 12 months. Surgery imposed an extra 746 Euro on the patient up to 6 months when compared to SRP. At 12 months, 46 Euro of this amount could be offset as a result of a reduced need for supportive care. Only 6 patients in the surgery group needed systemic antibiotics, whereas 14 patients in the SRP needed such additional treatment.
Although 700 Euro could be saved on average by performing SRP instead of surgery, the latter significantly reduced the need for supportive care and systemic antibiotics.
比较即刻手术与龈下刮治术和根面平整术(SRP)治疗晚期牙周病的效果,重点关注残留部位的发生率和成本效益(1);评估阿奇霉素在第二治疗阶段的辅助作用(2)。
39例患者(18例男性,21例女性;平均年龄:54.6岁)接受口腔卫生指导,并随机分为手术组(n = 19)或SRP组(n = 20)。6个月时存在残留牙周袋(≥6 mm)的患者接受这些部位的再次清创和全身性阿奇霉素治疗。治疗组随访至12个月,并根据临床反应参数和成本效益进行评估。使用椅旁时间评估治疗的经济影响。
就临床结果而言,两个治疗组同样有效,12个月时残留牙周袋均少于1%。与SRP相比,手术在6个月内使患者额外花费746欧元。在12个月时,由于对支持性护理的需求减少,这笔费用中的仅46欧元可得到抵消。手术组只有6例患者需要全身性抗生素,而SRP组有14例患者需要这种额外治疗。
尽管与手术相比,进行SRP平均可节省700欧元,但手术显著减少了对支持性护理和全身性抗生素的需求。