Tajima A, Aso Y, Ushiyama T, Hata M, Kambayashi T, Ohmi Y, Masuda H, Nakahara M, Kitagawa M, Suzuki A
Hinyokika Kiyo. 1986 Mar;32(3):477-85.
Allylestrenol at the daily dose of 50 mg was administered to 45 patients with benign prostatic hypertrophy. The treatment was performed for more than 12 weeks in 40 patients, and improvements, marked and moderate, were observed in 22 patients (55%) in the overall judgement. As side effects of this drug, decrease of potency was observed in 3 cases, decrease of libido in 1 case, pigmentation on breasts in 2 cases, palpitation in 2 cases, short breath in 1 case, and gastrointestinal symptoms in 1 case. However, these side effects were not serious. Our trial suggests that the treatment of benign prostatic hypertrophy with allylestrenol can be useful in urological clinics.
对45例良性前列腺增生患者给予每日剂量为50毫克的烯丙雌醇。40例患者接受了超过12周的治疗，总体判断显示，22例患者（55%）有明显和中度改善。作为该药物的副作用，3例出现性功能减退，1例出现性欲减退，2例乳房色素沉着，2例心悸，1例气短，1例胃肠道症状。然而，这些副作用并不严重。我们的试验表明，烯丙雌醇治疗良性前列腺增生在泌尿外科临床可能是有用的。
