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花生凝集素结合作为嗜酸性肉芽肿诊断的组织化学工具。

Peanut agglutinin binding as a histochemical tool for diagnosis of eosinophilic granuloma.

作者信息

Hajdu I, Zhang W, Gordon G B

出版信息

Arch Pathol Lab Med. 1986 Aug;110(8):719-21.

PMID:2425777
Abstract

Histochemical detection of peanut agglutinin binding performed on tissue sections in 11 cases of eosinophilic granuloma of bone revealed simultaneous appearance of the reaction product both at the cell surface and within the cytoplasm (in the Golgi area) of a vast majority of Langerhans' cells. Based on this unique characteristic of Langerhans' cells, peanut agglutinin binding assay may represent a simple and inexpensive tool for morphologic differentiation of eosinophilic granuloma or other types of histiocytosis X from other monocytic and histiocytic lesions in equivocal cases.

摘要

对11例骨嗜酸性肉芽肿组织切片进行花生凝集素结合的组织化学检测,结果显示,绝大多数朗格汉斯细胞的细胞表面和细胞质(高尔基体区域)均同时出现反应产物。基于朗格汉斯细胞的这一独特特征,在诊断不明确的病例中,花生凝集素结合试验可能是一种简单且经济的工具,用于嗜酸性肉芽肿或其他类型组织细胞增多症X与其他单核细胞和组织细胞病变的形态学鉴别。

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