对断奶体重、断奶后体重增加和 6 周体重选择的直接和相关反应在小鼠中。

Direct and correlated responses to selection for weaning weight, post-weaning weight gain and six-week weight in mice.

机构信息

Genetics Section, Ruakura Agricultural Research Centre, Private Bag, Hamilton, New Zealand.

出版信息

Theor Appl Genet. 1984 Jan;67(2-3):113-22. doi: 10.1007/BF00317015.

Abstract

Four lines of mice were formed from a common base population and selected for 37 generations for either increased 3-week weight (weaning weight), 6-week weight, 3-6 week gain, or maintained as a randomly bred control line. Realised heritability estimates for short-term (long-term) responses were 0.33±0.20 (0.07±0.10), 0.46±0.14 (0.26±0.09), 0.36±0.14 (0.24±0.11) for 3-week weight, 6-week weight and 3-6 week gain, respectively. Realised genetic correlations estimated from short-term (long-term) responses were 0.23±0.08 (0.35±0.10) between 3-week weight and 3-6 week gain; 0.82±0.04 (0.58±0.08) between 3-week weight and 6-week weight; and 0.81±0.04 (0.97±0.04) between 3-6 week gain and 6-week weight. The genetic correlation between 3-week weight and 6-week weight was asymmetric with a greater correlated response for 3-week weight when selecting for 6-week weight (1.06) than vice versa (0.63).

摘要

四条品系的小鼠是由一个共同的基础种群形成的，并经过 37 代的选择，以增加 3 周龄体重（断奶体重）、6 周龄体重、3-6 周增重，或维持为随机繁殖的对照品系。短期（长期）响应的实现遗传力估计值分别为 0.33±0.20（0.07±0.10）、0.46±0.14（0.26±0.09）、0.36±0.14（0.24±0.11），用于 3 周龄体重、6 周龄体重和 3-6 周增重。从短期（长期）响应中估计的实现遗传相关系数分别为 0.23±0.08（0.35±0.10），用于 3 周龄体重和 3-6 周增重之间；0.82±0.04（0.58±0.08），用于 3 周龄体重和 6 周龄体重之间；0.81±0.04（0.97±0.04），用于 3-6 周增重和 6 周龄体重之间。3 周龄体重和 6 周龄体重之间的遗传相关系数是不对称的，当选择 6 周龄体重时，3 周龄体重的相关响应更大（1.06），而不是相反（0.63）。