Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.
Muscle Nerve. 2014 Jun;49(6):804-8. doi: 10.1002/mus.24127. Epub 2014 Jan 27.
To evaluate the sensitivity of electrophysiologic assessments, we compared F-waves and motor and sensory nerve conduction studies (MNCS and SNCS) in patients with diabetes mellitus (DM).
We tested median, ulnar, tibial, and fibular nerves in 132 DM patients divided into those with and without clinical evidence of polyneuropathy.
Of 64 asymptomatic patients, 2 (3%) had MNCS or SNCS abnormalities, both of whom had F-wave changes, whereas 21 (33%) had only delayed F-waves, for a combined yield of 23 (36%). The corresponding values for 68 symptomatic patients consisted of 43 (63%), 14 (21%), and 57 (84%). In both groups, F-wave latency had a higher (P<0.05) frequency of abnormality than MNCS in all nerves. F-wave study also surpassed SNCS in lower limb nerves.
F-waves of the tibial and fibular nerves are the most sensitive measure to detect subclinical or overt diabetic polyneuropathy. Muscle Nerve 49: 804-808, 2014.
为了评估电生理评估的敏感性，我们比较了糖尿病（DM）患者的 F 波和运动及感觉神经传导研究（MNCS 和 SNCS）。
我们测试了 132 例 DM 患者的正中神经、尺神经、胫神经和腓总神经，将其分为有和无临床证据的多发性神经病患者。
64 例无症状患者中，2 例（3%）有 MNCS 或 SNCS 异常，均有 F 波改变，21 例（33%）仅有 F 波延迟，总检出率为 23%（36%）。68 例有症状患者的结果分别为 43 例（63%）、14 例（21%）和 57 例（84%）。在两组中，F 波潜伏期在所有神经中的异常频率均高于 MNCS（P<0.05）。F 波研究在下肢神经中也优于 SNCS。
胫神经和腓总神经的 F 波是检测亚临床或显性糖尿病多发性神经病最敏感的指标。《肌肉神经》49: 804-808, 2014.
