Gafoor Sameer, Franke Jennifer, Bertog Stefan, Boehm Patrick, Heuer Luisa, Gonzaga Maik, Bauer Janine, Braut Annkathrin, Lam Simon, Vaskelyte Laura, Hofmann Ilona, Sievert Horst
Cardiovascular Center, Frankfurt, Germany.
Catheter Cardiovasc Interv. 2014 Apr 1;83(5):805-10. doi: 10.1002/ccd.25297. Epub 2013 Dec 24.
To determine the procedural safety, safety, and efficacy of left atrial appendage (LAA) occlusion in octogenarians.
Elderly patients with atrial fibrillation (AF) often do not receive appropriate anticoagulation. LAA occlusion is an option for patients with AF and contraindications to anticoagulation. Not much is known about the procedural safety and clinical efficacy of LAA occlusion in the very elderly.
A retrospective review of LAA cases at our institution between 2002 and 2013 in patients 80 years of age or older was performed. Demographic, echocardiographic, procedural, and clinical follow-up data were collected.
Seventy-five cases were attempted in patients 80 years of age or older (average age 83.4 ± 2.8 years, 53.3% males). Hypertension, coronary artery disease, and heart failure were present in 96, 41.3, and 36%, respectively. Mean CHADS2 and CHA2DS-VASc scores were 3.3 and 5.2. Devices used included the WATCHMAN, ACP, PLAATO, Lariat, and Coherex devices, which were attempted in 34.7, 36, 17.3, 5.3, and 5.3%, respectively. Overall procedural success, safety endpoint, and 1-year device efficacy was 90.1, 3.9, and 97.4%, respectively.
LAA closure is a safe and efficacious method of stroke prevention in the very elderly with AF.
确定在八旬老人中进行左心耳封堵术的操作安全性、安全性及有效性。
老年房颤(AF)患者常未接受恰当的抗凝治疗。左心耳封堵术是房颤且有抗凝治疗禁忌证患者的一种选择。对于高龄患者左心耳封堵术的操作安全性及临床有效性了解不多。
对我院2002年至2013年80岁及以上患者的左心耳封堵病例进行回顾性分析。收集人口统计学、超声心动图、操作及临床随访数据。
对80岁及以上患者进行了75例封堵尝试(平均年龄83.4±2.8岁,男性占53.3%)。高血压、冠状动脉疾病和心力衰竭的发生率分别为96%、41.3%和36%。平均CHADS2和CHA2DS-VASc评分分别为3.3和5.2。使用的器械包括WATCHMAN、ACP、PLAATO、Lariat和Coherex器械,分别尝试了34.7%、36%、17.3%、5.3%和5.3%。总体操作成功率、安全终点及1年器械有效性分别为90.1%、3.9%和97.4%。
左心耳封堵术是高龄房颤患者预防卒中的一种安全有效的方法。