Zhang Hai-Yan, Wu Wei, Zhu Jin
Department of Gynecology, The Obstetrics and Gynecology Hospital, Shanghai Medical College, Fudan University No.419 Fangxie Road, Shanghai, China.
Int J Clin Exp Med. 2013 Oct 25;6(10):1010-4. eCollection 2013.
Invasive mole belongs to gestational trophoblastic neoplasm, which is a highly curable group of pregnancy-related tumors. However, approximately 20% of gestational trophoblastic tumors will be resistant to or relapsed after initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. It is still unclear which regimens are the most effective and least toxic. Here, we report a case of unilateral hydronephrosis presenting 1 week after a history of curettage because of a hydatidiform mole. With the combination treatments of chemotherapy and surgery, the patient was cured.
侵蚀性葡萄胎属于妊娠滋养细胞肿瘤，这是一组治愈率很高的妊娠相关肿瘤。然而，大约20%的妊娠滋养细胞肿瘤在初始化疗后会出现耐药或复发。这些耐药和复发病变需要进行挽救性化疗，可能还需要手术。目前仍不清楚哪种治疗方案最有效且毒性最小。在此，我们报告一例因葡萄胎刮宫术后1周出现单侧肾积水的病例。通过化疗和手术的联合治疗，患者得以治愈。
